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Article
LightGBM is an Effective Predictive Model for Postoperative Complications in Gastric Cancer: A Study Integrating Radiomics with Ensemble Learning
Postoperative complications of radical gastrectomy seriously affect postoperative recovery and require accurate risk prediction. Therefore, this study aimed to develop a prediction model specifically tailored ...
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Article
Differentiation between viral and autoimmune limbic encephalitis: a prospective cohort study with development and validation of a diagnostic model
Distinguishing between viral encephalitis (VE) and autoimmune limbic encephalitis (ALE) presents a clinical challenge due to the overlap in symptoms. We aimed to develop and validate a diagnostic prediction mo...
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Article
Open AccessReal-time procedure information sharing as a means to reduce perioperative anxiety in families of children undergoing elective surgery - a randomized controlled study
To investigate whether the surgical process information sharing system could alleviate the parental anxiety during a pediatric selective operation.
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Article
Open AccessAbrogating PDK4 activates autophagy-dependent ferroptosis in breast cancer via ASK1/JNK pathway
Targeting ferroptosis mediated by autophagy presents a novel therapeutic approach to breast cancer, a mortal neoplasm on the global scale. Pyruvate dehydrogenase kinase isozyme 4 (PDK4) has been denoted as a d...
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Article
Artificial intelligence–based three-dimensional templating for total joint arthroplasty planning: a sco** review
The purpose of this review is to evaluate the current status of research on the application of artificial intelligence (AI)–based three-dimensional (3D) templating in preoperative planning of total joint arthr...
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Article
Open AccessExploring the diagnostic value of ultrasound radiomics for neonatal respiratory distress syndrome
Neonatal respiratory distress syndrome (NRDS) is a prevalent cause of respiratory failure and death among newborns, and prompt diagnosis is imperative. Historically, diagnosis of NRDS relied mostly on typical ...
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Article
Patient-reported outcomes of mesh in minimally invasive (laparoscopic/robot-assisted) immediate subpectoral prosthesis breast reconstruction: a retrospective study
Although there is increasing interest in minimally invasive prosthesis breast reconstruction (PBR), whether meshes application in minimally invasive PBR can improve complications and cosmetic effects remains c...
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Article
Open AccessThe association between metabolic dysfunction-associated steatotic liver disease, cardiovascular and cerebrovascular diseases and the thickness of carotid plaque
The relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and atherosclerosis has been controversial, which has become a hit of recent research. The study aimed to explore the a...
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Article
Effectiveness of preserved vagal nerve in totally laparoscopy radical distal gastrectomy: a matched‐paired cohort analysis
The aim of this retrospective matched‐paired cohort study was to clarify the effectiveness of preserving the vagus nerve in totally laparoscopic radical distal gastrectomy (TLDG).
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Article
Open Accessm1A Regulatory gene signatures are associated with certain immune cell compositions of the tumor microenvironment and predict survival in kidney renal clear cell carcinoma
Adenosine N1 methylation (m1A) of RNA, a type of post-transcriptional modification, has been shown to play a significant role in the progression of cancer. The objective of the current research was to analyze ...
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Article
Open AccessA real-world cost-effectiveness study of vancomycin versus linezolid for the treatment of late-onset neonatal sepsis in the NICU in China
Currently, the detection rates of methicillin-resistant S. aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS) in the blood cultures of neonates with sepsis exceed the national av...
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Article
Open AccessEffects of empowerment education on the self-management and self-efficacy of liver transplant patients: a randomized controlled trial
Despite the increasing survival rates, liver transplant patients experience numerous postoperative complications and encounter significant challenges in long-term self-management. This study aims to examine th...
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Article
Open AccessDNAJB7 is dispensable for male fertility in mice
DNAJBs are highly conserved proteins that are involved in various biological processes. Although several DNAJBs are highly expressed in the testis, the function of DNAJB7 in spermatogenesis and male fertility ...
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Article
Open AccessEmerging phagocytosis checkpoints in cancer immunotherapy
Cancer immunotherapy, mainly including immune checkpoints-targeted therapy and the adoptive transfer of engineered immune cells, has revolutionized the oncology landscape as it utilizes patients’ own immune sy...
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Article
Deubiquitylation of Rab35 by USP32 promotes the transmission of imatinib resistance by enhancing exosome secretion in gastrointestinal stromal tumours
Imatinib is a tyrosine kinase inhibitor that is widely used to combat gastrointestinal stromal tumours (GISTs). However, secondary resistance to imatinib is an important challenge in GIST treatment. Recent stu...
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Article
Open AccessThe influence of day 3 embryo cell number on the clinical pregnancy and live birth rates of day 5 single blastocyst transfer from frozen embryo transfer cycles
To evaluate the influence of day 3 embryo cell number on the clinical pregnancy and live birth rates of day 5 single blastocyst transfer in frozen embryo transfer (FET) cycles.
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Article
Development and Results of the First Certification Examination in the American Board of Medical Specialties Neurocritical Care Subspecialty
This article reviews the development of the American Board of Medical Specialties subspecialty in neurocritical care (NCC) and describes the requirements for certification and the results of the first certific...
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Article
ASO Visual Abstract: Safety and feasibility of Minimally Invasive (Laparoscopic/Robotic-Assisted) Nipple-Sparing Mastectomy Combined with Prosthesis Breast Reconstruction in Breast Cancer—A Single-Center Retrospective Study
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Article
Safety and Feasibility of Minimally Invasive (Laparoscopic/Robotic-Assisted) Nipple-Sparing Mastectomy Combined with Prosthesis Breast Reconstruction in Breast Cancer: A Single-Center Retrospective Study
Minimally invasive (robotic or laparoscopic-assisted) nipple-sparing mastectomy combined with prosthesis breast reconstruction (NSM–PBR) is associated with smaller scars and greater patient satisfaction. Howev...
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Article
Open AccessThe joint effects of physical activity and air pollution on type 2 diabetes in older adults
Older adults with type 2 diabetes are at higher risk of develo** common geriatric syndromes and have a lower quality of life. To prevent type 2 diabetes in older adults, it’s unclear whether the health benef...