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Open AccessKLF4 defines the efficacy of the epidermal growth factor receptor inhibitor, erlotinib, in triple-negative breast cancer cells by repressing the EGFR gene
Triple-negative breast cancer (TNBC) is characterized by high rates of recurrence and poor overall survival. This is due, in part, to a deficiency of targeted therapies, making it essential to identify therape...
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Molecular and Cellular Developments in Heart Valve Development and Disease
The prevalence of heart valve disease is estimated at 2.5% and this number is likely to increase with the steady rise in life expectancy and associated degenerative pathology. Affected individuals suffer signi...