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  1. Article

    Open Access

    Revealing spatiotemporal inequalities, hotspots, and determinants in healthcare resource distribution: insights from hospital beds panel data in 2308 Chinese counties

    Ensuring universal health coverage and equitable access to health services requires a comprehensive understanding of spatiotemporal heterogeneity in healthcare resources, especially in small areas. The absence...

    Chao Song, Lina Fang, Mingyu **e, Zhangying Tang, Yumeng Zhang… in BMC Public Health (2024)

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  2. No Access

    Article

    Efficient Soluble Expression and Purification of Recombinant Human Acidic Fibroblast Growth Factor from Escherichia coli via Fusion with a Novel Collagen-like Protein Scl2

    Human acidic fibroblast growth factor (haFGF) is a multifunctional protein involved in regulating a wide range of cellular processes. As a potent therapeutic agent, it is highly desirable to produce recombinan...

    Inam ur Rahman, Wei Liu, Zhang Wei, Lina Fang… in Applied Biochemistry and Biotechnology (2020)

  3. No Access

    Article

    Production of Levulinic Acid via Cellulose Conversion Over Metal Oxide-Loaded MOF Catalysts in Aqueous Medium

    In this study, Zr-MOF material (UiO-66) was modified with different metal oxides (CeO2, Ga2O3, and CoO) and employed in the conversion of cellulose to levulinic acid (LA) in aqueous medium. The research results s...

    Kaifeng Wang, Ya Liu, Wufeng Wu, Yu Chen, Lina Fang, Wanbin Li… in Catalysis Letters (2020)

  4. No Access

    Article

    Distribution of Products from Catalytic Conversion of Cellulose Over Metal-Modified Hierarchical H-ZSM-5 in Aqueous Media

    A series of metal-modified hierarchical M/H-ZSM-5 catalysts were prepared for catalytic conversion of cellulose in an aqueous medium. Characterization of the catalysts showed that the impregnation of metal int...

    **aoxia He, Yu Chen, Ya Liu, Lina Fang, Zeng Chen, Hongbing Ji in Catalysis Letters (2019)

  5. No Access

    Article

    An aptamer-based four-color fluorometic method for simultaneous determination and imaging of alpha-fetoprotein, vascular endothelial growth factor-165, carcinoembryonic antigen and human epidermal growth factor receptor 2 in living cells

    The extraordinary fluorescence quenching capability of graphene oxide (GO) was coupled to the specific recognition capability of aptamers to design a four-color fluorescent nanoprobe for multiplexed detection ...

    Jiayao Xu, Wenting Chen, Ming Shi, Yong Huang, Lina Fang, Shulin Zhao… in Microchimica Acta (2019)

  6. No Access

    Article

    Simultaneous Determination of Procaspase Activating Compound 1 and Permeability Markers in Intestinal Perfusion Samples and Application to a Rat Intestinal Absorption Study

    A sensitive and simple HPLC method for simultaneous determination of PAC-1 (first procaspase-activating compound), phenol red, and permeability markers (carbamazepine and furosemide) in perfusion samples was d...

    Lina Fang, Qiudi Wang, Kaishun Bi, Xu Zhao in Chromatographia (2016)

  7. No Access

    Article

    Timosaponin B-II ameliorates scopolamine-induced cognition deficits by attenuating acetylcholinesterase activity and brain oxidative damage in mice

    Timosaponin B-II (TB-II) is a main active saponin isolated from the rhizome of Anemarrhena asphodeloides Bge., which is widely used in traditional Chinese medicine. In this study, the effect of TB-II on learning ...

    Xu Zhao, Chunmei Liu, Yu Qi, Lina Fang, Jie Luo, Kaishun Bi… in Metabolic Brain Disease (2016)

  8. No Access

    Article

    Kinetic Study of the Degradation of PAC-1 and Identification of a Degradation Product in Alkaline Condition

    A selective and validated stability-indicating LC method was developed for the kinetic study of the degradation of PAC-1, which was carried out in aqueous solutions at 37, 60, 80 and 100 °C with pH 1.5–9.0. Se...

    Zhen Song, **aohui Chen, Di Zhang, Lei Ren, Lina Fang, Weiming Cheng… in Chromatographia (2009)

  9. No Access

    Chapter and Conference Paper

    Using Segmentation Method for Better Ontology Inference

    Ontologies become more and more big, which is an important factor of low-efficient reasoning. In this paper, we propose an ontology segmentation method for alleviating the inference burden. The method is based...

    Youwei Xu, Shengqun Tang, Yang Xu, Ruliang **ao… in Advances in Intelligent Web Mastering (2007)

  10. No Access

    Chapter and Conference Paper

    Discovering Web Services Based on Match History

    This paper presents an approach for distributed discovery of web services based on the match history. A service routing table (SRT) is introduced into each registry node to record the history of matches for se...

    Yang Xu, Shengqun Tang, Youwei Xu, Ruliang **ao… in Advances in Intelligent Web Mastering (2007)

  11. No Access

    Chapter and Conference Paper

    Using Categorial Context-SHOIQ(D+) DL to Migrate Between the Context-Aware Scenes

    An important issue in semantic web ontology application is how to improve ontological evolvement to fit the semantics of the unceasingly changing context. This paper presents a context-based formalism- Context...

    Ruliang **ao, Shengqun Tang, Ling Li, Lina Fang… in Web Information Systems – WISE 2006 (2006)

  12. No Access

    Chapter and Conference Paper

    A Workflow Language for Grid Services in OGSI-Based Grids

    Workflow is a critical part of the emerging Grid Computing Environments and captures the linkage of constituent services together in a hierarchical fashion to build larger composite services. As an indispensab...

    Yan Yang, Shengqun Tang, Wentao Zhang… in Grid and Cooperative Computing - GCC 2004 (2004)