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  1. No Access

    Article

    Triclosan-conjugated, Lipase-responsive Polymeric Micelles for Eradication of Staphylococcal Biofilms

    Bacterial biofilms present a significant challenge in treating drug-resistant infections, necessitating the development of innovative nanomedicines. In this study, we introduce triclosan-conjugated, lipase-res...

    Yan-Qiang Huang, Yuan-Feng Li, Yong Liu, Lin-Qi Shi in Chinese Journal of Polymer Science (2024)

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    Article

    A Dynamic Covalent Bonding-based Nanoplatform for Intracellular Co-Delivery of Protein Drugs and Chemotherapeutics with Enhanced Anti-Cancer Effect

    Efficient intracellular delivery of protein drugs is critical for protein therapy. The combination of protein drugs with chemotherapeutics represents a promising strategy in enhancing anti-cancer effect. Howev...

    Sai-Nan Liu, Jia-Hui Meng, Li-Yun Cui, Hua Chen… in Chinese Journal of Polymer Science (2024)

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    Article

    Bioinspired Self-assembly Nanochaperone Inhibits Tau-Derived PHF6 Peptide Aggregation in Alzheimer’s Disease

    After repeated frustrations with amyloid beta (Aβ)-targeted clinical trials for Alzheimer’s disease (AD) in recent years, the therapeutic focus of AD has gradually shifted from Aβ to tau protein. The misfolding a...

    Lin Zhu, Ming-Qing Zhang, Hao-Ren **g, **-Peng Zhang… in Chinese Journal of Polymer Science (2022)

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    Article

    Responsive Polymeric Nanoparticles for Biofilm-infection Control

    With the emergence of multidrug resistance (MDR) in many pathogens, bacterial infections are becoming a growing threat to public health. The frightening scenario is due largely to the formation of biofilms, in...

    Lin-Zhu Su, Yong Liu, Yuan-Feng Li, Ying-Li An… in Chinese Journal of Polymer Science (2021)