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Article
EEMNet: an end-to-end efficient model for PCB surface tiny defect detection
The miniaturization of electronic products has led to the denser and more crowded wiring on printed circuit boards (PCBs), which has made PCB defects smaller and more difficult to detect. Moreover, the complex...
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Article
Open AccessAlteration of serum bile acid profiles of HBV-related hepatocellular carcinoma identified by LC–MS/MS
Hepatocellular carcinoma closely related to metabolic disorders is a common and aggressive liver malignancy. The dysregulation of bile acid homeostasis has emerged as a key factor for the development and progr...
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Article
Association between chitinase-3-like protein 1 and metabolic-associated fatty liver disease in patients with type 2 diabetes mellitus
Early identification of liver fibrosis is essential for the prognosis of metabolic-associated fatty liver disease (MAFLD), particularly in type 2 diabetes mellitus (T2DM) patients. Here, we explored the associ...
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Article
Osteocyte-derived sclerostin impairs cognitive function during ageing and Alzheimer’s disease progression
Ageing increases susceptibility to neurodegenerative disorders, such as Alzheimer’s disease (AD). Serum levels of sclerostin, an osteocyte-derived Wnt–β-catenin signalling antagonist, increase with age and inh...
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Article
Open AccessJMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation
In epigenetic modification, histone modification and DNA methylation coordinate the regulation of spermatogonium. Not only can methylcytosine dioxygenase 1 (TET1) function as a DNA demethylase, converting 5-me...
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Article
Biosynthesizing lignin dehydrogenation polymer to fabricate hybrid hydrogel composite with hyaluronic acid for cartilage repair
Lignin possesses a number of functional groups including phenolic hydroxyl and methoxy groups, which grant its bioactivity for the fabrication of bio-polymer-based composites in bone tissue engineering applica...
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Article
Open AccessNeoadjuvant sintilimab in combination with concurrent chemoradiotherapy for locally advanced gastric or gastroesophageal junction adenocarcinoma: a single-arm phase 2 trial
In this multicenter, single-arm phase 2 trial (ChiCTR1900024428), patients with locally advanced gastric/gastroesophageal junction cancers receive one cycle of sintilimab (anti-PD1) and chemotherapy (S-1 and n...
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Article
Ultrafast growth of wafer-scale fold-free bilayer graphene
Bilayer graphene provides a versatile platform for exploring a variety of intriguing phenomena and shows much promise for applications in electronics, optoelectronics, etc. Controlled growth of large-area bila...
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Article
Open AccessFast synthesis of large-area bilayer graphene film on Cu
Bilayer graphene (BLG) is intriguing for its unique properties and potential applications in electronics, photonics, and mechanics. However, the chemical vapor deposition synthesis of large-area high-quality b...
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Article
Publisher Correction: 2D fin field-effect transistors integrated with epitaxial high-k gate oxide
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Article
2D fin field-effect transistors integrated with epitaxial high-k gate oxide
Precise integration of two-dimensional (2D) semiconductors and high-dielectric-constant (k) gate oxides into three-dimensional (3D) vertical-architecture arrays holds promise for develo** ultrascaled transistor...
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Article
Open AccessUniform thin ice on ultraflat graphene for high-resolution cryo-EM
Cryo-electron microscopy (cryo-EM) visualizes the atomic structure of macromolecules that are embedded in vitrified thin ice at their close-to-native state. However, the homogeneity of ice thickness, a key fac...
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Article
Open AccessFunctionalized graphene grids with various charges for single-particle cryo-EM
A major hurdle for single particle cryo-EM in structural determination lies in the specimen preparation impaired by the air-water interface (AWI) and preferential particle-orientation problems. In this work, w...
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Article
Open AccessIntegrated wafer-scale ultra-flat graphene by gradient surface energy modulation
The integration of large-scale two-dimensional (2D) materials onto semiconductor wafers is highly desirable for advanced electronic devices, but challenges such as transfer-related crack, contamination, wrinkl...
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Article
Open AccessConstruction and validation of a predictive model for hepatocellular carcinoma based on serum markers
Early hepatocellular carcinoma (HCC) detection with non-invasive biomarkers remains an unmet clinical need. We aimed to construct a predictive model based on the pre-diagnostic levels of serum markers to predi...
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Article
Open AccessLarge-area transfer of two-dimensional materials free of cracks, contamination and wrinkles via controllable conformal contact
The availability of graphene and other two-dimensional (2D) materials on a wide range of substrates forms the basis for large-area applications, such as graphene integration with silicon-based technologies, wh...
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Article
Open AccessThe changes of the calf-vein deformation and femoral vein peak velocity during ankle pump exercise with or without graduated compression stockings
To analyze the changes of lower limb hemodynamics parameters before and after wearing graduated compression stockings (GCS) during ankle pump exercise in patients preparing for arthroplastic surgery.
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Article
Open AccessInfluence of the Maximum Blur Radius on Depth Sensor Based on Liquid Crystal Lens
This paper describes how the maximum blur radius affects the depth results by depth from the defocus (DFD) method based on liquid crystal (LC) lens. Boundary frequency is determined by the maximum blur radius....
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Chapter and Conference Paper
Generalized Snell’s Law and Its Verification by Metasurface
The generalized Snell’s law derived based on Fermat’s principle and the boundary conditions of continuity are introduced in this paper. The 3D format of generalized Snell’s law is also demonstrated. The genera...
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Article
Salmonella enteritidis Hcp distribute in the cytoplasm and regulate TNF signaling pathway in BHK-21 cells
Hemolysin-coregulated protein (Hcp) of Salmonella enteritidis is known to be a structural and effector protein of the T6SS, but little is known about the role of Hcp in host cells. In this study, Hcp was expresse...