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Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

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  1. Article

    Author Correction: Origin and evolution of the octoploid strawberry genome

    In the version of this article originally published, author Joshua R. Puzey was incorrectly listed as having affiliation 7 (School of Plant Sciences, University of Arizona, Tucson, AZ, USA); affiliation 6 (Dep...

    Patrick P. Edger, Thomas J. Poorten, Robert VanBuren in Nature Genetics (2019)

  2. Article

    Open Access

    Origin and evolution of the octoploid strawberry genome

    Cultivated strawberry emerged from the hybridization of two wild octoploid species, both descendants from the merger of four diploid progenitor species into a single nucleus more than 1 million years ago. Here...

    Patrick P. Edger, Thomas J. Poorten, Robert VanBuren in Nature Genetics (2019)

  3. Article

    Open Access

    Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses

    The RNA-binding protein (RBP) TAF15 is implicated in amyotrophic lateral sclerosis (ALS). To compare TAF15 function to that of two ALS-associated RBPs, FUS and TDP-43, we integrate CLIP-seq and RNA Bind-N-Seq ...

    Katannya Kapeli, Gabriel A. Pratt, Anthony Q. Vu, Kasey R. Hutt in Nature Communications (2016)

  4. Article

    Open Access

    Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression

    A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce trans...

    Ruben G. de Bruin, Lily Shiue, Jurriën Prins, Hetty C. de Boer in Nature Communications (2016)