Skip to main content

and
  1. Article

    Open Access

    Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses

    The RNA-binding protein (RBP) TAF15 is implicated in amyotrophic lateral sclerosis (ALS). To compare TAF15 function to that of two ALS-associated RBPs, FUS and TDP-43, we integrate CLIP-seq and RNA Bind-N-Seq ...

    Katannya Kapeli, Gabriel A. Pratt, Anthony Q. Vu, Kasey R. Hutt in Nature Communications (2016)

  2. Article

    Open Access

    Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression

    A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce trans...

    Ruben G. de Bruin, Lily Shiue, Jurriën Prins, Hetty C. de Boer in Nature Communications (2016)