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Article
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
Myotonic dystrophy is a CUG repeat expansion disease and mice deficient in MBNL1, an RNA binding protein, show many characteristics of the disease. Comparison of gene expression profiles of two mouse models of...
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Article
Exploring functional relationships between components of the gene expression machinery
Eukaryotic gene expression requires the coordinated activity of many macromolecular machines including transcription factors and RNA polymerase, the spliceosome, mRNA export factors, the nuclear pore, the ribo...