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    Article

    Quantitative immunodetection of key elements of polyphosphoinositide signal transduction in osteoblasts from arthritic patients shows a direct correlation with cell proliferation

    Phosphoinositides play an essential role in diverse cellular functions such as cell proliferation, cytoskeletal regulation, intracellular vesicle trafficking, motility, cell metabolism and death. Alteration of...

    Nicoletta Zini, Gina Lisignoli, Liliana Solimando in Histochemistry and Cell Biology (2005)

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    Protocol

    Single and Double Colloidal Gold Labeling in Postembedding Immunoelectron Microscopy

    Immunocytochemistry is the most diffuse technique to visualize and localize specific biochemical components in cell compartments and tissues. With this method the antigens are tagged by antibodies that can be ...

    Nicoletta Zini, Liliana Solimando in Cell Cycle Control and Dysregulation Proto… (2004)

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    Article

    IL1-β and TNF-α induce changes in the nuclear polyphosphoinositide signalling system in osteoblasts similar to that occurring in patients with rheumatoid arthritis: an immunochemical and immunocytochemical study

    Osteoarthritis (OA) and rheumatoid arthritis (RA) are common joint diseases that can lead to destruction of cartilage and structural changes in the subchondral bone. In this study we show by western blot and q...

    Nicoletta Zini, Gina Lisignoli, Liliana Solimando in Histochemistry and Cell Biology (2003)