5 Result(s)
within
Lihui Yang
Life Sciences, general
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Article
Open AccessLoss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
Hepatocellular carcinoma (HCC) is a deadly malignancy with high genetic heterogeneity. TP53 mutation and c-MET activation are frequent events in human HCCs. Here, we discovered that the simultaneous mutations in
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Article
Open AccessCorrection: In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects
Following the publication of this article, the authors noticed that Fig. 5c in the original manuscript is incorrect due to an error in image handling during the creation of the figure. Specifically, the image ...
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Article
Open AccessIn vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects
In vitro cultured autologous mesenchymal stem cells (MSCs) within passage 5 have been approved for clinical application in stem cell-based treatment of cartilage defects. However, their chondrogenic potential has...
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Article
Open AccessNerve growth factor from Chinese cobra venom stimulates chondrogenic differentiation of mesenchymal stem cells
Growth factors such as transforming growth factor beta1 (TGF-β1), have critical roles in the regulation of the chondrogenic differentiation of mesenchymal stem cells (MSCs), which promote cartilage repair. Howeve...
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Article
Open AccessNotch activity opposes ras-induced differentiation during the second mitotic wave of the develo** Drosophilaeye
EGF receptor acts through Ras and the MAPK cascade to trigger differentiation and maintain survival of most of cell types in the Drosophila retina. Cell types are specified sequentially by separate episodes of EG...
