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Article
Open AccessESS MS-G3D: extension and supplement shift MS-G3D network for the assessment of severe mental retardation
Automated mental retardation (MR) assessment is potential for improving the diagnostic efficiency and objectivity in clinical practice. Based on the researches on abnormal behavior characteristics of patients ...
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Article
Development of a CRISPR/Cpf1 system for multiplex gene editing in Aspergillus oryzae
CRISPR/Cas technology is a powerful tool for genome engineering in Aspergillus oryzae as an industrially important filamentous fungus. Previous study has reported the application of the CRISPR/Cpf1 system based o...
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Article
Open AccessPsychosocial factors of insomnia in depression: a network approach
Insomnia symptoms in patients with major depressive disorder (MDD) are common and deleterious. Childhood trauma, personality traits, interpersonal distress, and social support contribute to insomnia, but how t...
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Article
Effect of hydrostatic pressure on the mechanical, thermodynamic, and optical properties of orthorhombic WAlB
To better explain the effect of pressure on the physicochemical properties of orthorhombic WAlB, the mechanical, anisotropy of sound velocity, and optical properties are discussed using density functional theo...
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Article
Open AccessSuperior temporal gyrus and cerebellar loops predict nonsuicidal self-injury in major depressive disorder patients by multimodal neuroimaging
In major depressive disorder (MDD) patients, nonsuicidal self-injury (NSSI) is a common comorbidity, and it is important to clarify the underlying neurobiology. Here, we investigated the association of NSSI wi...
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Article
Graphene-wrapped multiloculated nickel ferrite: A highly efficient electromagnetic attenuation material for microwave absorbing and green shielding
Dedicating to the exploration of efficient electromagnetic (EM) absorption and electromagnetic interference (EMI) shielding materials is the main strategy to solve the EM radiation issues. The development of m...
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Article
Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis
This meta-analysis was conducted to estimate the overall association between maternal exposure to pesticides and risk of ASD in offspring. PubMed, EMBASE, Web of Science, and the PsycINFO were searched until D...
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Article
Open AccessOverall trend towards headache remission during the COVID-19 pandemic among Chinese patients with pre-existing headache highlights the role of family support
The global status of the COVID-19 pandemic is not optimistic. This is a particularly vulnerable time for patients with pre-existing headache disorders. The present study aimed to investigate the impact of the ...
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Article
Open AccessUltrasound-guided parasternal intercostal nerve block for postoperative analgesia in mediastinal mass resection by median sternotomy: a randomized, double-blind, placebo-controlled trial
Ultrasound-guided parasternal intercostal nerve block is rarely used for postoperative analgesia, and its value remains unclear. This study aimed to evaluate the effectiveness of ultrasound-guided parasternal ...
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Article
Open AccessAcute psychological effects of Coronavirus Disease 2019 outbreak among healthcare workers in China: a cross-sectional study
To study the acute psychological effects of Coronavirus Disease 2019 (COVID-19) outbreak among healthcare workers (HCWs) in China, a cross-sectional survey was conducted among HCWs during the early period of C...
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Article
Open AccessAutophagy-dependent cell cycle arrest in esophageal cancer cells exposed to dihydroartemisinin
Dihydroartemisinin (DHA), a derivate of artemisinin, is an effective antimalarial agent. DHA has been shown to exert anticancer activities to numerous cancer cells in the past few years, while the exact molecu...
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Article
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells
Occupational and tobacco exposure to aromatic amines (AAs) including 4-aminobiphenyl (4-ABP) and 2-naphthylamine (2-NA) are associated with bladder cancer (BC) risk. Several epidemiological studies have also r...
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Article
Open AccessGuiding migration of transplanted glial progenitor cells in the injured spinal cord
Transplantation of glial-restricted progenitors (GRPs) is a promising strategy for generating a supportive environment for axon growth in the injured spinal cord. Here we explored the possibility of producing ...
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Article
Optimization of ultrasonic-assisted extraction of flavonoid from Portulaca oleracea L. by response surface methodology and chemical composition analysis
Optimization of ultrasonic extraction of Portulaca oleracea L. flavonoids (POF) was investigated using single-factor experimentation combined with response surface methodology. The optimal conditions for the high...
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Article
Subchronic olanzapine treatment decreases the expression of pancreatic glucose transporter 2 in rat pancreatic β cells
Olanzapine is a second generation antipsychotic. A common side effect in humans is weight gain, but the mechanisms are mostly unknown.
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Article
Open AccessNegative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder
Major depressive disorder (MDD) is a long-term, recurrent condition that often takes a chronic course. It seems imperative that research should be focused on gaining a better understanding of what predicts rec...
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Article
Multidimensional CAT Item Selection Methods for Domain Scores and Composite Scores: Theory and Applications
Multidimensional computer adaptive testing (MCAT) can provide higher precision and reliability or reduce test length when compared with unidimensional CAT or with the paper-and-pencil test. This study compared...
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Article
Exploitation of Malus EST-SSRs and the utility in evaluation of genetic diversity in Malus and Pyrus
A total of 8117 suitable SSR-contaning ESTs were acquired by screening from a Malus EST database, among which dinudeotide SSRs were the most abundant repeat motif, within which, CT/TC followed by AG/GA were predo...
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Article
Open AccessProduct inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties
Lysophosphatidylcholines (lysoPCs) are products of phospholipase A2 (PLA2) enzyme activity, and like the enzyme, have a direct role in toxic inflammatory responses in variety of organ systems. Paradoxically, r...
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Chapter
Methods and Models for Vertical Scaling
When one test form is significantly and intentionally more difficult than another, a link that places scores from these test forms on a common scale might be called a “vertical” link, and the scale on which th...
