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Article
Ruthenium–dihydroartemisinin complex: a promising new compound for colon cancer prevention via G1 cell cycle arrest, apoptotic induction, and adaptive immune regulation
Artemisinin (ART) and its derivatives are important antimalaria agents and have received increased attention due to their broad biomedical effects, such as anticancer and anti-inflammation activities. Recently...
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Article
Effects of dihydroartemisinin, a metabolite of artemisinin, on colon cancer chemoprevention and adaptive immune regulation
Artemisinin (ART) is an anti-malaria natural compound with a moderate anticancer action. As a metabolite of ART, dihydroartemisinin (DHA) may have stronger anti-colorectal cancer (CRC) bioactivities. However, ...
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Article
Open AccessFirst exploration of radiation temperatures of the laser spot, re-emitting wall and entire hohlraum drive source
This study explores the radiation field temperatures introduced by the laser spot, the re-emitting wall in a hohlraum and the entire hohlraum drive source. This investigation, which is the first of its kind, i...
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Article
Type 1 interferon-induced IL-7 maintains CD8+ T-cell responses and homeostasis by suppressing PD-1 expression in viral hepatitis
Type 1 interferon (IFN-I) promotes antigen-presenting cell maturation and was recently shown to induce hepatic IL-7 production during infection. Herein, we further explored the underlying mechanisms used by IF...
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Chapter
SerpinB1: A Global Regulator of Neutrophil Homeostasis
SerpinB1 is an inhibitory serpin, which is broadly expressed at highly variable levels. It is encoded by an ancient gene—possibly the extant homologue of the serpin gene at the root of the clade B tree. Studie...
