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Article
Prediction of ROS1 and TRKA/B/C occupancy in plasma and cerebrospinal fluid for entrectinib alone and in DDIs using physiologically based pharmacokinetic (PBPK) modeling approach
Entrectinib (ENT) is a potent c-ros oncogene 1(ROS1) and neurotrophic tyrosine receptor kinase (NTRKA/B/C) inhibitor. To determine the optimum dosage of ENT using ROS1 and NTRKA/B/C occupancy in plasma and cer...
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Article
Critical Area Identification of Potential Soil Loss in a Typical Watershed of the Three Gorges Reservoir Region
Identifying critical soil loss-prone areas is necessary to better control soil loss in the **angxi watershed, the river basin nearest the Three Gorges Dam. A crucial element of this scheme is the development o...