32 Result(s)

Article

Map** and candidate gene analysis of QTLs for grain shape in a rice chromosome segment substitution line Z485 and breeding of SSSLs

Grain shape is one of the most important factors that affects rice yield. Cloning novel grain shape genes and analyzing their genetic mechanisms are crucial for high yield breeding. In this study, a slender gr...

**g You, Li Ye, Dachuan Wang, Yi Zhang, Wenwen **ao, Mi Wei… in Molecular Breeding (2024)

Article

TESOS: an integrated approach for uniform mesoscale imaging

Yu Wang, Li Ye in Cell Research (2024)

Article

Systematic analyzing a five- miRNA panel and its diagnostic value of plasma expression in colorectal cancer

Aberrant expression of miRNAs have been implicated in cancers, but the role of miRNAs in colorectal cancer (CRC) remains need to be elucidated. This study aimed to identify miRNAs that related to colorectal ca...

Si-Qi Li, Li-Ye **e, Zheng-Min Cai, Hao-Tang Wei, Ming-Zhi **e… in Molecular Biology Reports (2023)

Article

The roles of ETS transcription factors in liver fibrosis

E26 transformation specific or E twenty-six (ETS) protein family consists of 28 transcription factors, five of which, named ETS1/2, PU.1, ERG and EHF, are known to involve in the development of liver fibrosis,...

Li-Ye Zhang, Yong Tan, **ao-Jie Luo, Jiang-Feng Wu, Yi-Ran Ni in Human Cell (2023)

Article

Effect and Mechanism of Cotrimoxazole Against Talaromyces marneffei in vitro

Talaromyces marneffei (formerly Penicillium marneffei) is an important thermally dimorphic fungus endemic which is characterized by one of the most frequent opportunistic infections in HIV/AIDS patients, mainly p...

Jie Chen, Rongfeng Chen, Wudi Wei, Fengxiang Qin, **u Chen, **hao He… in Mycopathologia (2022)

Article

The production of bacterial cellulose in Gluconacetobacter xylinus regulated by luxR overexpression of quorum sensing system

Quorum sensing is a mechanism that facilitates cell-to-cell communication. Through signal molecular density for signal recognition, which leads to the regulation of some physiological and biochemical functions. G...

Tian-Zhen Zhang, Ling-Pu Liu, Li Ye, Wen-Chao Li… in Applied Microbiology and Biotechnology (2021)

Article

Fungichromin production by Streptomyces sp. WP-1, an endophyte from Pinus dabeshanensis, and its antifungal activity against Fusarium oxysporum

In this study, we isolated an endophytic Streptomyces sp. strain, WP-1, from surface-sterilized barks of Pinus dabeshanensis, an endangered Chinese plant. WP-1 showed strong antifungal activity against diverse pa...

Cheng Peng, Duopeng An, Wen-**n Ding… in Applied Microbiology and Biotechnology (2020)

Article

Autophagy suppression enhances DNA damage and cell death upon treatment with PARP inhibitor Niraparib in laryngeal squamous cell carcinoma

Although poly (ADP-ribose) polymerase (PARP) inhibitors, as anti-tumor drugs targeting the DNA damage response (DDR), have been used for the therapy of various tumors, few researches reported their effect on l...

Yunxiang Ji, Qian Wang, Qian Zhao, Shuwei Zhao… in Applied Microbiology and Biotechnology (2019)

Article

C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells

Sorafenib as an effective multikinase inhibitor has been approved for the clinical treatment against advanced hepatocellular carcinoma (HCC). HCC treatment requires usually combined therapy because of its comp...

Shanshan Jiang, Qian Wang, Meiqing Feng… in Applied Microbiology and Biotechnology (2017)

Article

Production of a therapeutic protein by fusing it with two fragments of the carboxyl-terminal peptide of human chorionic gonadotropin β-subunit in Pichia pastoris

To produce a therapeutic protein (endostatin) by fusion with two fragments of the carboxyl-terminal peptide (CTP) of the human chorionic gonadotropin β-subunit in Pichia pastoris.

Baolong Wang, **n Wang, Chris Wayne, **angxiang Wang, Lei Han… in Biotechnology Letters (2016)

Article

Isolation and characterization of LEAFY COTYLEDON 1-LIKE gene related to embryogenic competence in Citrus sinensis

A member of the LEAFY COTYLEDON gene family encoding a HAP3 (heme activated protein 3) subunit of the CCAAT box-binding factor was isolated and termed as Citrus sinensis LEAFY COTYLEDON 1-LIKE (C...

Shi-** Zhu, Jun Wang, Jun-li Ye… in Plant Cell, Tissue and Organ Culture (PCTO… (2014)

Article

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

CLARITY enables the chemical transformation of intact biological tissues into a hydrogel–tissue hybrid. The hybrid samples can be interrogated using light and macromolecular labels, whilst retaining fine struc...

Raju Tomer, Li Ye, Brian Hsueh, Karl Deisseroth in Nature Protocols (2014)

Article

Tumor necrosis therapy antibody interleukin-2 fusion protein elicits prolonged and targeted antitumor effects in vivo

Interleukin-2 (IL-2) is one of the most successful cytokines applied in tumor immunotherapy because of its ability to stimulate potent cellular immune response. The life-threatening toxicity of vascular leak s...

Li Ye, Jiajun Fan, Xunlong Shi, Qun Tao, Dan Ye… in Applied Microbiology and Biotechnology (2014)

Article

Enhancement of microbial hydroxylation of 13-ethyl-gon-4-ene-3,17-dione by Metarhizium anisopliae using nano-liposome technique

The introduction of 11α-hydroxy to 13-ethyl-gon-4-ene-3,17-dione (GD) by microbial transformation is a key step in the synthesis of oral contraceptive desogestrel, while low substrate solubility and uptake int...

Meiqing Feng, Ziwei Liao, Lei Han, Jiyang Li… in Journal of Industrial Microbiology & Biote… (2014)