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    Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis

    Pancreatic β-cells are particularly susceptible to fatty-acid-induced endoplasmic reticulum (ER) stress and apoptosis. To understand how β-cells sense fatty acid stimuli and translate into a long-term adaptive...

    Mun-Wai Cheong, Li-Hua Kuo, Yi-Ning Cheng, Pei-Jane Tsai… in Journal of Molecular Medicine (2015)