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  1. Article

    Open Access

    LSM14B controls oocyte mRNA storage and stability to ensure female fertility

    Controlled mRNA storage and stability is essential for oocyte meiosis and early embryonic development. However, how to regulate mRNA storage and stability in mammalian oogenesis remains elusive. Here we showed...

    Li-Ying Shan, Yu Tian, Wen-**ang Liu, Hai-Tao Fan in Cellular and Molecular Life Sciences (2023)

  2. Article

    Open Access

    Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution

    Functional characterization of pseudouridine (Ψ) in mammalian mRNA has been hampered by the lack of a quantitative method that maps Ψ in the whole transcriptome. We report bisulfite-induced deletion sequencing...

    Qing Dai, Li-Sheng Zhang, Hui-Lung Sun, Kinga Pajdzik, Lei Yang in Nature Biotechnology (2023)

  3. No Access

    Article

    Non-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome

    Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary a...

    Wei-Wei Li, Yan Yang, Qi-Gang Dai, Li-Li Lin, Tong **e, Li-Li He in Metabolomics (2018)

  4. No Access

    Article

    A method for isolating and culturing vascular smooth muscle cells from porcine cerebral arteries

    Cerebral blood vessels have unique properties when compared to most peripheral vascular beds. One such property is that large cerebral vessels are involved in the regulation of cerebral vascular resistance. St...

    Hong Tao, Li-Ming Zhang, Manuel R. Castresana, Walter H. Newman in Methods in Cell Science (1996)