300 Result(s)

Article

A novel surgical scheme for hepatectomy in hepatocellular carcinoma patients with clinically significant portal hypertension

Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new su...

Jia-zhou Ye, Hua-ze Lu, Can Zeng, Guo Lei, **ao-bo Wang, Jie Chen, Tao Bai… in BMC Cancer (2024)

Article

The Naples prognostic score serves as a predictor and prognostic indicator for cancer survivors in the community

Inflammation, malnutrition, and cancer are intricately interconnected. Despite this, only a few studies have delved into the relationship between inflammatory malnutrition and the risk of death among cancer su...

Chaoqun Liang, Chao Zhang, Jun Song, Lin Yan, Yun **ao, Nan Cheng, Han Wu… in BMC Cancer (2024)

Article

UHPLC-HRMS-based Multiomics to Explore the Potential Mechanisms and Biomarkers for Colorectal Cancer

Understanding the metabolic changes in colorectal cancer (CRC) and exploring potential diagnostic biomarkers is crucial for elucidating its pathogenesis and reducing mortality. Cancer cells are typically deriv...

Xuancheng Wang, Xuan Guan, Ying Tong, Yunxiao Liang, Zongsheng Huang… in BMC Cancer (2024)

Article

Ferroptosis is a protective factor for the prognosis of cancer patients: a systematic review and meta-analysis

Cancer is a leading global cause of death. Conventional cancer treatments like surgery, radiation, and chemotherapy have associated side effects. Ferroptosis, a nonapoptotic and iron-dependent cell death, has ...

Shen Li, Kai Tao, Hong Yun, Jiaqing Yang, Yuanling Meng, Fan Zhang, Xuelei Ma in BMC Cancer (2024)

Article

Pragmatic nationwide master observational trial based on genomic alterations in advanced solid tumors: KOrean Precision Medicine Networking Group Study of MOlecular profiling guided therapy based on genomic alterations in advanced Solid tumors (KOSMOS)-II study protocol KCSG AL-22–09

Next-generation sequencing (NGS) has been introduced to many Korean institutions to support molecular diagnostics in cancer since 2017, when it became eligible for reimbursement by the National Health Insuranc...

Sun Young Kim, Jee Hyun Kim, Tae-Yong Kim, Sook Ryun Park, Shinkyo Yoon… in BMC Cancer (2024)

Article

Retraction Note: Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer

**-Yun Li, Wen-**ao Huang, **ao Zhou, Jie Chen, Zan Li in BMC Cancer (2024)

Article

The vasculogenic mimicry related signature predicts the prognosis and immunotherapy response in renal clear cell carcinoma

Clear cell carcinoma of the kidney is a common urological malignancy characterized by poor patient prognosis and treatment outcomes. Modulation of vasculogenic mimicry in tumor cells alters the tumor microenvi...

Yuming Gu, Qinqin Huang, Yun Wang, Haixia Wang, Zhenhua **ang, Yu Xu… in BMC Cancer (2024)

Article

Retraction Note: KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis

Changhwan Yoon, Jun Lu, Yukyung Jun, Yun-Suhk Suh, Bang-** Kim… in BMC Cancer (2024)

Article

Evaluation of an artificial intelligence-based clinical trial matching system in Chinese patients with hepatocellular carcinoma: a retrospective study

Artificial intelligence (AI)-assisted clinical trial screening is a promising prospect, although previous matching systems were developed in English, and relevant studies have only been conducted in Western co...

Kunyuan Wang, Hao Cui, Yun Zhu, **aoyun Hu, Chang Hong, Yabing Guo… in BMC Cancer (2024)

Article

Treatment for locally resectable stage IIIC1r cervical cancer: surgery or chemoradiotherapy?

The aim of this study was to compare the therapeutic value and treatment-related complications of radical hysterectomy with those of concurrent chemoradiotherapy (CCRT) for locally resectable (T1a2–T2a1) stage...

Mei-ling Zhong, Yin-chuan Liu, Jian-tong Yang, Ya-nan Wang, Mei-hong Ao… in BMC Cancer (2024)

Article

Differential efficacy of tyrosine kinase inhibitors according to the types of EGFR mutations and agents in non-small cell lung cancer: a real-world study

Both first and second-generation EGFR-TKIs are recommended in advanced NSCLC with common EGFR mutations. However, there are few data on the difference in efficacy of EGFR-TKIs based on the type of EGFR mutatio...

Tae-Hwan Kim, **-Hyuk Choi, Mi Sun Ahn, Hyun Woo Lee, Seok Yun Kang… in BMC Cancer (2024)

Article

Comprehensive assessment of the genetic characteristics of small for gestational age newborns in NICU: from diagnosis of genetic disorders to prediction of prognosis

In China, ~1,072,100 small for gestational age (SGA) births occur annually. These SGA newborns are a high-risk population of developmental delay. Our study aimed to evaluate the genetic profile of SGA newborns...

Hui **ao, Huiyao Chen, **ang Chen, Yulan Lu, Bingbing Wu, Huijun Wang… in Genome Medicine (2023)

Article

Pre-operative clonal hematopoiesis is related to adverse outcome in lung cancer after adjuvant therapy

Clonal hematopoiesis (CH) frequently progresses after chemotherapy or radiotherapy. We evaluated the clinical impact of preoperative CH on the survival outcomes of patients with non-small cell lung cancer (NSC...

Jae Kwang Yun, Sugyeong Kim, Hongyul An, Geun Dong Lee, Hyeong Ryul Kim… in Genome Medicine (2023)

Article

Acute ischemia induces spatially and transcriptionally distinct microglial subclusters

Damage in the ischemic core and penumbra after stroke affects patient prognosis. Microglia immediately respond to ischemic insult and initiate immune inflammation, playing an important role in the cellular inj...

Huiya Li, Pinyi Liu, Bing Zhang, Zengqiang Yuan, Mengdi Guo, **nxin Zou… in Genome Medicine (2023)

Article

The role of computed tomography features in assessing response to neoadjuvant chemotherapy in locally advanced gastric cancer

To compare the computed tomography (CT) images of patients with locally advanced gastric cancer (GC) before and after neoadjuvant chemotherapy (NAC) in order to identify CT features that could predict patholog...

Chengzhi Wei, Yun He, Ma Luo, Guoming Chen, Runcong Nie, **aojiang Chen… in BMC Cancer (2023)

Article

Annotation of cell types (ACT): a convenient web server for cell type annotation

The advancement of single-cell sequencing has progressed our ability to solve biological questions. Cell type annotation is of vital importance to this process, allowing for the analysis and interpretation of ...

Fei Quan, **n Liang, Mingjiang Cheng, Huan Yang, Kun Liu, Shengyuan He… in Genome Medicine (2023)

Article

Influence on therapeutic outcome of platelet count at diagnosis in patients with de novo non-APL acute myeloid leukemia

Platelet (PLT) count at diagnosis plays an important role in cancer development and progression in solid tumors. However, it remains controversial whether PLT count at diagnosis influences therapeutic outcome ...

Yujiao Zhang, Quan Wu, Baoyi Yuan, Yun Huang, Ling Jiang, Fang Liu, ** Yan… in BMC Cancer (2023)

Article

The optimal intravesical maintenance chemotherapy scheme for the intermediate-risk group non-muscle-invasive bladder cancer

Although the current European Association of Urology(EAU) guideline recommends that patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) should accept intravesical chemotherapy or Calmett...

Jian-**n Chen, Wen-Ting Huang, Qing-Yun Zhang, Cheng-En Deng, Jue-ling Wei… in BMC Cancer (2023)

Article

Study protocol for prospective multi-institutional phase III trial of standard of care therapy with or without stereotactic ablative radiation therapy for recurrent ovarian cancer (SABR-ROC)

Efforts have been made to investigate the role of salvage radiotherapy (RT) in treating recurrent ovarian cancer (ROC). Stereotactic ablative radiation therapy (SABR) is a state-of-the-art therapy that uses in...

Yong Bae Kim, Hwa Kyung Byun, Chan Woo Wee, Ho** Kim, Seyoung Kim… in BMC Cancer (2023)

Article

Overexpression of SH2D1A promotes cancer progression and is associated with immune cell infiltration in hepatocellular carcinoma via bioinformatics and in vitro study

SH2 domain containing 1A (SH2D1A) expression has been linked to cancer progression. However, the functions of SH2D1A in hepatocellular carcinoma (HCC) have not been reported.

Qian-Ming **ang, Ni Jiang, Yue-Feng Liu, Yuan-Biao Wang, De-An Mu, Rong Liu… in BMC Cancer (2023)