1,643 Result(s)

Article

Importance of FSH-releasing protein and inhibin in erythrodifferentiation

Inhibin is a hypophysiotropic hormone which selectively suppresses the secretion of pituitary follicle-stimulating hormone. It has been isolated from gonadal fluids and characterized as a protein heterodimer ...

John Yu, Li-en Shao, Victor Lemas, Alice L. Yu, Joan Vaughan, Jean Rivier… in Nature (1987)

Article

When big is beautiful

S. R. Kulkarni, M. Shao, C. A. Haniff in Nature (1991)

Article

Induced long-range order in crosslinked ‘one-dimensional’ stacks of fluid monolayers

Ordinary crystals are characterized by long-range translational order in all three dimensions. In lower-dimensional systems, in contrast, translational order is destroyed through the ‘Landau–Peierls instabilit...

Gerald C. L. Wong, Wim H. de Jeu, Henry Shao, Keng S. Liang, Rudolf Zentel in Nature (1997)

Article

Role of the histone deacetylase complex in acute promyelocytic leukaemia

Non-liganded retinoic acid receptors (RARs) repress transcription of target genes by recruiting the histone deacetylase complex^1,2,3 through a class of silencing mediators termed SMRT or N-CoR⁴,⁵. Mutant forms of...

Richard J. Lin, Laszlo Nagy, Satoshi Inoue, Wenlin Shao, Wilson H. Miller Jr… in Nature (1998)

Article

Interdomain communication regulating ligand binding by PPAR-γ

Binding to receptors in the cell nucleus is crucial for the action of lipophilic hormones and ligands. PPAR-γ (for peroxisome proliferator-activated receptor) is a nuclear hormone receptor that mediates adipoc...

Dalei Shao, Shamina M. Rangwala, Shannon T. Bailey, Samuel L. Krakow… in Nature (1998)

Article

Selective amplification by auto- and cross-catalysis in a replicating peptide system

Self-replication has been demonstrated in synthetic chemical systems based on oligonucleotides^{1,2,3,4,5,6,7}, peptides^8,9,10,11,12 and complementary molecules without natural analogues^13,14,15,16. However, within ...

Shao Yao, Indraneel Ghosh, Reena Zutshi, Jean Chmielewski in Nature (1998)

Article

Fringe is a glycosyltransferase that modifies Notch

Notch receptors function in highly conserved intercellular signalling pathways that direct cell-fate decisions, proliferation and apoptosis in metazoans. Fringe proteins can positively and negatively modulate ...

Daniel J. Moloney, Vladislav M. Panin, Stuart H. Johnston, Jihua Chen, Li Shao… in Nature (2000)

Article

Genome sequence of enterohaemorrhagic Escherichia coli O157:H7

The bacterium Escherichia coli O157:H7 is a worldwide threat to public health and has been implicated in many outbreaks of haemorrhagic colitis, some of which included fatalities caused by haemolytic uraemic synd...

Nicole T. Perna, Guy Plunkett III, Valerie Burland, Bob Mau, Jeremy D. Glasner… in Nature (2001)

Article

An efficient room-temperature silicon-based light-emitting diode

There is an urgent requirement for an optical emitter that is compatible with standard, silicon-based ultra-large-scale integration (ULSI) technology¹. Bulk silicon has an indirect energy bandgap and is therefore...

Wai Lek Ng, M. A. Lourenço, R. M. Gwilliam, S. Ledain, G. Shao, K. P. Homewood in Nature (2001)

Article

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins

A goal of modern biology is to identify the physical interactions that define ‘functional modules’¹ of proteins that govern biological processes. One essential regulatory process is the maintenance of master regu...

Andrew J. Saurin, Zhaohui Shao, Hediye Erdjument-Bromage, Paul Tempst… in Nature (2001)

Article

HDAC6 is a microtubule-associated deacetylase

Reversible acetylation of α-tubulin has been implicated in regulating microtubule stability and function¹. The distribution of acetylated α-tubulin is tightly controlled and stereotypic. Acetylated α-tubulin is m...

Charlotte Hubbert, Amaris Guardiola, Rong Shao, Yoshiharu Kawaguchi, Akihiro Ito… in Nature (2002)

Article

Sequence and analysis of rice chromosome 4

Rice is the principal food for over half of the population of the world. With its genome size of 430 megabase pairs (Mb), the cultivated rice species Oryza sativa is a model plant for genome research¹. Here we re...

Qi Feng, Yujun Zhang, Pei Hao, Shengyue Wang, Gang Fu, Yucheng Huang, Ying Li… in Nature (2002)

Article

A distance of 133–137 parsecs to the Pleiades star cluster

Nearby ‘open’ clusters of stars (those that are not gravitationally bound) have played a crucial role in the development of stellar astronomy because, as a consequence of the stars having a common age, they pr...

**aopei Pan, M. Shao, S. R. Kulkarni in Nature (2004)

Article

A high-performance cathode for the next generation of solid-oxide fuel cells

Fuel cells directly and efficiently convert chemical energy to electrical energy¹. Of the various fuel cell types, solid-oxide fuel cells (SOFCs) combine the benefits of environmentally benign power generation wi...

Zong** Shao, Sossina M. Haile in Nature (2004)

Article

A thermally self-sustained micro solid-oxide fuel-cell stack with high power density

Solid oxide fuel cells are not suitable for powering small portable devices, mainly because if built small, they need heat input to keep them running. A new approach to fuel-cell design tackles that problem he...

Zong** Shao, Sossina M. Haile, Jeongmin Ahn, Paul D. Ronney, Zhongliang Zhan… in Nature (2005)

Article

Millennial- and orbital-scale changes in the East Asian monsoon over the past 224,000 years

Stalactites, stalagmites and the many other forms of mineral deposits found in caves are a mainstay of climate studies, recording oxygen isotope ratios in limestone laid down over time. That pattern links to t...

Yong** Wang, Hai Cheng, R. Lawrence Edwards, **nggong Kong, **aohua Shao… in Nature (2008)

Article

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

Recent studies in mice identified multipotent embryonic ISL1⁺ (Islet 1 expressing) progenitor cells as capable of contributing to all of the major cell types in the heart. Human cardiogenesis is thought to involv...

Lei Bu, **n Jiang, Silvia Martin-Puig, Leslie Caron, Shenjun Zhu, Ying Shao… in Nature (2009)