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  1. Article

    Open Access

    Exploring in vivo cholesterol-mediated interactions between activated EGF receptors in plasma membrane with single-molecule optical tracking

    The first step in many cellular signaling processes occurs at various types of receptors in the plasma membrane. Membrane cholesterol can alter these signaling pathways of living cells. However, the process in...

    Chien Y. Lin, Jung Y. Huang, Leu-Wei Lo in BMC Biophysics (2016)

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  2. No Access

    Article

    Formation of CdSe/CdS/ZnS-Au/SiO2 dual-yolk/shell nanostructures through a Trojan-type inside-out etching strategy

    In this work we report the development of a rapid and selective etching strategy to synthesize a dual-yolk/shell nanostructure consisting of semiconductor-metal hybrid nanocrystals and hollow SiO2 for the first t...

    Ching-Mao Huang, Shih-Hsun Cheng, U-Ser Jeng, Chung-Shi Yang, Leu-Wei Lo in Nano Research (2012)

  3. No Access

    Chapter and Conference Paper

    A Micro-Light Guide System for Measuring Oxygen by Phosphorescence Quenching

    Oxygen is an essential metabolite and alterations in tissue oxygen levels cause or contribute to many pathophysiological states. An effective method to non-invasively measure the oxygen concentration in biolog...

    Leu-Wei Lo, David F. Wilson in Oxygen Transport to Tissue XXV (2003)

  4. No Access

    Chapter and Conference Paper

    Nanoparticulates in vivo

    Nanoparticulates may have wide and important applications in clinical diagnosis and therapeutics. This report describes the effect of a particular type of nanosphere-carbon 60 (C60) on microglia activation and on...

    Leu-Wei Lo, Pi-Ju Tsai, SamHong-Yi Huang… in Frontiers in Biomedical Engineering (2003)

  5. No Access

    Chapter

    A New, Water Soluble, Phosphor for Oxygen Measurements in Vivo

    Oxygen dependent quenching of phosphorescence is an optical method for non-invasive measurements of oxygen in the microvasculature of tissue (see 3-7,10,11). it is unique among the oxygen measuring methods in tha...

    Leu-Wei Lo, Sergei A. Vinogradov, Cameron J. Koch… in Oxygen Transport to Tissue XIX (1997)

  6. No Access

    Chapter

    Oxygen Dependent Quenching of Phosphorescence

    Oxygen dependent quenching of phosphorescence has now been in use as a method for measuring oxygen for about 10 years. As expected for a new technique, these years have seen a rapid evolution of every aspect o...

    David F. Wilson, Sergei Vinogradov, Leu-Wei Lo, Lu Huang in Oxygen Transport to Tissue XVII (1996)