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Microfluidic platform for the quantitative analysis of leukocyte migration signatures

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  1. Article

    Open Access

    Convergent and Divergent Migratory Patterns of Human Neutrophils inside Microfluidic Mazes

    Neutrophils are key cellular components of the innate immune response and characteristically migrate from the blood towards and throughout tissues. Their migratory process is complex, guided by multiple chemoa...

    Leo Boneschansker, Julianne Jorgensen, Felix Ellett, David M. Briscoe… in Scientific Reports (2018)

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  2. Article

    Open Access

    Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions

    The deterioration of whole blood ex vivo represents a logistical hurdle in clinical and research settings. Here, a cocktail preservative is described that stabilizes leukocyte viability and erythrocyte morphology...

    Rebecca D. Sandlin, Keith H. K. Wong, Leo Boneschansker… in Scientific Reports (2017)

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  3. Article

    Translational implications of endothelial cell dysfunction in association with chronic allograft rejection

    Advances in therapeutics have dramatically improved short-term graft survival, but the incidence of chronic rejection has not changed in the past 20 years. New insights into mechanism are sorely needed at this...

    Sarah Bruneau, Johannes Wedel, Fadi Fakhouri, Hironao Nakayama… in Pediatric Nephrology (2016)

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