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Article
Open AccessConvergent and Divergent Migratory Patterns of Human Neutrophils inside Microfluidic Mazes
Neutrophils are key cellular components of the innate immune response and characteristically migrate from the blood towards and throughout tissues. Their migratory process is complex, guided by multiple chemoa...
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Article
Open AccessPreservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions
The deterioration of whole blood ex vivo represents a logistical hurdle in clinical and research settings. Here, a cocktail preservative is described that stabilizes leukocyte viability and erythrocyte morphology...
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Article
Translational implications of endothelial cell dysfunction in association with chronic allograft rejection
Advances in therapeutics have dramatically improved short-term graft survival, but the incidence of chronic rejection has not changed in the past 20 years. New insights into mechanism are sorely needed at this...
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Article
Microfluidic platform for the quantitative analysis of leukocyte migration signatures
Leukocyte migration into tissues is characteristic of inflammation. It is usually measured in vitro as the average displacement of populations of cells towards a chemokine gradient, not acknowledging other patter...
