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  1. Article

    Open Access

    Convergent and Divergent Migratory Patterns of Human Neutrophils inside Microfluidic Mazes

    Neutrophils are key cellular components of the innate immune response and characteristically migrate from the blood towards and throughout tissues. Their migratory process is complex, guided by multiple chemoa...

    Leo Boneschansker, Julianne Jorgensen, Felix Ellett, David M. Briscoe in Scientific Reports (2018)

  2. Article

    Open Access

    Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions

    The deterioration of whole blood ex vivo represents a logistical hurdle in clinical and research settings. Here, a cocktail preservative is described that stabilizes leukocyte viability and erythrocyte morphology...

    Rebecca D. Sandlin, Keith H. K. Wong, Leo Boneschansker in Scientific Reports (2017)

  3. No Access

    Article

    Microfluidic platform for the quantitative analysis of leukocyte migration signatures

    Leukocyte migration into tissues is characteristic of inflammation. It is usually measured in vitro as the average displacement of populations of cells towards a chemokine gradient, not acknowledging other patter...

    Leo Boneschansker, Jun Yan, Elisabeth Wong, David M. Briscoe in Nature Communications (2014)