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Article

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

The protein kinase Akt plays a pivotal role in cellular processes. However, its isoforms’ distinct functions have not been resolved to date, mainly due to the lack of suitable biochemical and cellular tools. A...

Lena Quambusch, Laura Depta, Ina Landel, Melissa Lubeck… in Nature Communications (2021)