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  1. Article

    Open Access

    Safety and efficacy of combination of suberoylamilide hydroxyamic acid and mitomycin C in reducing pro-fibrotic changes in human corneal epithelial cells

    Corneal haze post refractive surgery is prevented by mitomycin c (MMC) treatment though it can lead to corneal endothelial damage, persistent epithelial defects and necrosis of cells. Suberanilohydroxamic acid...

    Rohit Shetty, Nimisha Rajiv Kumar, Murali Subramani, Lekshmi Krishna in Scientific Reports (2021)

  2. Article

    Open Access

    Resveratrol reverses the adverse effects of bevacizumab on cultured ARPE-19 cells

    Age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR) are one of the major causes of blindness caused by neo-vascular changes in the retina. Intravitreal anti-VEGF injections are ...

    Murali Subramani, Murugeswari Ponnalagu, Lekshmi Krishna in Scientific Reports (2017)

  3. Article

    Open Access

    Nanostructured scaffold as a determinant of stem cell fate

    The functionality of stem cells is tightly regulated by cues from the niche, comprising both intrinsic and extrinsic cell signals. Besides chemical and growth factors, biophysical signals are important compone...

    Lekshmi Krishna, Kamesh Dhamodaran, Chaitra Jayadev in Stem Cell Research & Therapy (2016)

  4. No Access

    Article

    Synthesis and characterization of biodegradable poly (ethylene glycol) and poly (caprolactone diol) end capped poly (propylene fumarate) cross linked amphiphilic hydrogel as tissue engineering scaffold material

    Biodegradable poly (caprolactone diol-co-propylene fumarate-co-ethylene glycol) amphiphilic polymer with poly (ethylene glycol) and poly (caprolactone diol) chain ends (PCL–PPF–PEG) was prepared. PCL–PPF–PEG u...

    Lekshmi Krishna, Muthu Jayabalan in Journal of Materials Science: Materials in Medicine (2009)