8 Result(s)

Article

Characterization of HIV variants from paired Cerebrospinal fluid and Plasma samples in primary microglia and CD4⁺ T-cells

Despite antiretroviral therapy (ART), HIV persistence in the central nervous system (CNS) continues to cause a range of cognitive impairments in people living with HIV (PLWH). Upon disease progression, transmi...

Stephanie B. H. Gumbs, Arjen J. Stam, Tania Mudrikova… in Journal of NeuroVirology (2024)

Article

Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies

While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of a...

Jord C. Stam, Steven de Maat, Dorien de Jong, Mathia Arens… in Scientific Reports (2022)

Article

Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses

HIV persistence in the CNS despite antiretroviral therapy may cause neurological disorders and poses a critical challenge for HIV cure. Understanding the pathobiology of HIV-infected microglia, the main viral ...

Stephanie B. H. Gumbs, Raphael Kübler, Lavina Gharu… in Journal of NeuroVirology (2022)

Article

Proceedings of the Frontiers of Retrovirology Conference 2016

Oral presentations

Irena Zurnic, Sylvia Hütter, Ute Lehmann, Nicole Stanke, Juliane Reh… in Retrovirology (2016)

Article

Post transcriptional regulation of HIV-1 gene expression by MATR3, PSF and Rev

Lavina Gharu, Ania Kula, Maryana Bardina, Alessandro Marcello in Retrovirology (2013)