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  1. Article

    Open Access

    Progressive erythrocytosis under lenvatinib treatment in patients with advanced hepatocellular carcinoma

    This manuscript reports on the occurrence of early and frequent erythrocytosis in advanced hepatocellular carcinoma (HCC) patients treated with lenvatinib.

    Laurence Legros, Alina Pascale, Catherine Guettier in Cancer Chemotherapy and Pharmacology (2023)

  2. No Access

    Article

    Long-term outcome of imatinib 400 mg compared to imatinib 600 mg or imatinib 400 mg daily in combination with cytarabine or pegylated interferon alpha 2a for chronic myeloid leukaemia: results from the French SPIRIT phase III randomised trial

    The STI571 prospective randomised trial (SPIRIT) French trial is a four-arm study comparing imatinib (IM) 400 mg versus IM 600 mg, IM 400 mg + cytarabine (AraC), and IM 400 mg + pegylated interferon alpha2a (P...

    Francois Guilhot, Françoise Rigal-Huguet, Joëlle Guilhot in Leukemia (2021)

  3. No Access

    Article

    Low prevalence of JAK2 V617F mutation in patients with thrombosis and normal blood counts: a retrospective impact study

    To determine the prevalence of the V617F Janus Kinase 2 (JAK2) mutation in patients with thrombosis without other biological signs of underlying myeloproliferative neoplasm (MPN) and identify associated risk fact...

    Michaël Levraut, Laurence Legros in Journal of Thrombosis and Thrombolysis (2020)

  4. No Access

    Article

    Treatment of myelodysplastic syndromes with excess of blasts by bevacizumab is well tolerated and is associated with a decrease of VEGF plasma level

    Myelodysplastic syndromes (MDS) are associated with increased bone marrow vascularity and increased levels of various angiogenic factors including Vascular Endothelial Growth Factor (VEGF) which is implicated ...

    Laurence Legros, Bohrane Slama, Jean-Michel Karsenti, Norbert Vey in Annals of Hematology (2012)