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  1. Article

    Open Access

    Immunotherapy in breast cancer: an overview of current strategies and perspectives

    Recent progress in immunobiology has led the way to successful host immunity enhancement against breast cancer. In triple-negative breast cancer, the combination of cancer immunotherapy based on PD-1/PD-L1 imm...

    Véronique Debien, Alex De Caluwé, **aoxiao Wang in npj Breast Cancer (2023)

  2. Article

    Open Access

    Neo-CheckRay: radiation therapy and adenosine pathway blockade to increase benefit of immuno-chemotherapy in early stage luminal B breast cancer, a randomized phase II trial

    Residual breast cancer after neo-adjuvant chemotherapy (NACT) predicts disease outcome and is a surrogate for survival in aggressive breast cancer (BC) subtypes. Pathological complete response (pCR) rate, howe...

    Alex De Caluwé, Laurence Buisseret, Philip Poortmans, Dirk Van Gestel in BMC Cancer (2021)

  3. Article

    Open Access

    Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer

    Breast cancer (BC) immune infiltrates play a critical role in tumor progression and response to treatment. Besides stromal tumor infiltrating lymphocytes (sTILs) which have recently reached level 1B evidence a...

    Iris Nederlof, Davide De Bortoli, Yacine Bareche, Bastien Nguyen in Breast Cancer Research (2019)