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    Chapter

    Cannabis Use Disorder

    Adolescents and adults increasingly view cannabis as harmless. While the majority can use cannabis without harm, there are many potential problems including decline in educational or occupational functioning a...

    Samer N. Narouze, Caroline A. MacCallum, Lauren de Freitas in Cannabinoids and Pain (2021)

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    Chapter

    Cannabinoids as a Substitute for Opioids: Basic Science and Clinical Evidence

    Opioid overdose (illicit, prescription, nonmedical prescription) is the leading cause of accidental death in the United States. Alternative analgesics are warranted among chronic pain patients given the associ...

    Caroline A. MacCallum, Lauren de Freitas, Lauren Eadie in Cannabinoids and Pain (2021)

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    Chapter

    Cannabinoids and Adolescence

    Adolescence is a period for cortical maturation and neuronal development, particularly among frontal areas pertaining to executive function, decision-making, and reasoning. For these reasons, the adolescent br...

    Caroline A. MacCallum, Lauren de Freitas in Cannabinoids and Pain (2021)

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    Chapter

    Cannabinoid-Related Adverse Events and Impairment

    In addition to therapeutic benefits, cannabis also causes cognitive and psychomotor impairment in some individuals. Common acute adverse events can be cannabinoid-specific, such as those related to THC (e.g., ...

    Caroline A. MacCallum, Lauren de Freitas, Lindsay A. Lo in Cannabinoids and Pain (2021)

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    Chapter

    Cannabinoids and Mental Health Risks

    Recreational cannabis use has been associated with the development of psychosis; as such, there are numerous biopsychosocial risks and vulnerabilities to consider. The Diagnostic and Statistical Manual 5th Editio...

    Caroline A. MacCallum, Lauren de Freitas, Shaohua Lu in Cannabinoids and Pain (2021)

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    Chapter

    Cannabinoid-Based Medicines: Dosing, Titration & Monitoring

    Variations in cannabis formulations and methods of administration influence dosing, titration, and monitoring methodology. Smoking/vaporization, oral, oromucosal, and topical routes of administration each have...

    Caroline A. MacCallum, Lauren de Freitas, Lindsay A. Lo in Cannabinoids and Pain (2021)