-
Article
Inhibiting fatty acid synthesis overcomes colistin resistance
Treating multidrug-resistant infections has increasingly relied on last-resort antibiotics, including polymyxins, for example colistin. As polymyxins are given routinely, the prevalence of their resistance is ...
-
Article
Open AccessInterplay between eutrophication and climate warming on bacterial communities in coastal sediments differs depending on water depth and oxygen history
Coastal aquatic systems suffer from nutrient enrichment, which results in accelerated eutrophication effects due to increased microbial metabolic rates. Climate change related prolonged warming will likely acc...
-
Article
Open AccessThe molecular basis of regulation of bacterial capsule assembly by Wzc
Bacterial extracellular polysaccharides (EPSs) play critical roles in virulence. Many bacteria assemble EPSs via a multi-protein “Wzx-Wzy” system, involving glycan polymerization at the outer face of the cytop...
-
Article
Open AccessFeasibility of optical coherence tomography angiography to assess changes in retinal microcirculation in ovine haemorrhagic shock
This study aimed to investigate the feasibility of optical coherence tomography angiography (OCT-A) for quantitative analysis of flow density to assess changes in retinal perfusion in an experimental model of ...