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Article
Open AccessDonor template delivery by recombinant adeno-associated virus for the production of knock-in mice
The ability of recombinant adeno-associated virus to transduce preimplantation mouse embryos has led to the use of this delivery method for the production of genetically altered knock-in mice via CRISPR-Cas9. ...
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Article
Open AccessKIT is dispensable for physiological organ vascularisation in the embryo
Blood vessels form vast networks in all vertebrate organs to sustain tissue growth, repair and homeostatic metabolism, but they also contribute to a range of diseases with neovascularisation. It is, therefore,...
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Article
Erythro-myeloid progenitors contribute endothelial cells to blood vessels
The earliest blood vessels in mammalian embryos are formed when endothelial cells differentiate from angioblasts and coalesce into tubular networks. Thereafter, the endothelium is thought to expand solely by p...
