3 Result(s)
within
Lasse Pakanen
Forensic Medicine
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Article
Open AccessPresumed adverse events in health care are a frequent indication for medico-legal autopsy in Finland
The medico-legal autopsy is an essential tool in investigating deaths caused by an adverse event in health care, for both clinical risk management and for professional liability issues. However, there are no s...
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Article
Open AccessRNU6B, a frequent reference in miRNA expression studies, differentiates between deaths caused by hypothermia and chronic cardiac ischemia
Here, we tested the usefulness of small non-coding RNAs as references in quantitative RT-PCR expression analyses in hypothermia and chronic cardiac ischemia as the primary causes of death. Cq values of RNU6B, ...
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Article
Victims of lethal hypothermia have decreased levels of thrombomodulin in myocardium and urine
Severe cold stress has been shown to cause changes in the expression and secretion of thrombomodulin (TM), an endothelial protein regulating haemostasis and inflammation. To further evaluate TM as a cold stres...
