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Article
Open AccessExtra-abdominal trocar and instrument detection for enhanced surgical workflow understanding
Video-based intra-abdominal instrument tracking for laparoscopic surgeries is a common research area. However, the tracking can only be done with instruments that are actually visible in the laparoscopic image...
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Article
Open AccessTowards multimodal graph neural networks for surgical instrument anticipation
Decision support systems and context-aware assistance in the operating room have emerged as the key clinical applications supporting surgeons in their daily work and are generally based on single modalities. T...
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Article
Open AccessModel-based individual life-spanning documentation in visceral surgery: a proof of concept
Surgical documentation has many implications. However, its primary function is to transfer information about surgical procedures to other medical professionals. Thereby, written reports describing procedures i...
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Article
Open AccessAudio-based event detection in the operating room
Even though workflow analysis in the operating room has come a long way, current systems are still limited to research. In the quest for a robust, universal setup, hardly any attention has been given to the di...
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Article
Open AccessCorrection to: Versatile end effector for laparoscopic robotic scrub nurse
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Article
Open AccessVersatile end effector for laparoscopic robotic scrub nurse
Integrating robotic scrub nurses in the operating room has the potential to help overcome staff shortages and limited use of available operating capacities in hospitals. Existing approaches of robotic scrub nu...
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Chapter
The Establishment of the International Police Relations Section at the German Police University—An Investment in the Present and the Future
There has been a growing need for highly qualified leading personnel in International Police Missions (IPMs). The German police has a particular interest in filling these positions with its own officers. To ac...
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Article
Open AccessComprehensive genomic profiling in routine clinical practice leads to a low rate of benefit from genotype-directed therapy
Describe a single-center real-world experience with comprehensive genomic profiling (CGP) to identify genotype directed therapy (GDT) options for patients with malignancies refractory to standard treatment opt...
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Article
Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study
Amplification and high levels of NOTCH ligand expression have been identified in several types of pediatric brain tumors. A phase I trial of weekly MK-0752, an oral inhibitor of gamma-secretase, was conducted ...
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Article
Therapy resistance mechanisms in Ewing’s sarcoma family tumors
Ewing’s sarcoma family tumors are aggressive small round cell malignancies that arise in bone or soft tissues in adolescents and young adults. The addition of chemotherapy to local control measures has remarka...
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Chapter
Pediatric Neuroblastoma: Treatment with Oral Irinotecan and Temozolomide
New strategies are needed to improve outcomes for children with high-risk neuroblastoma, as fewer than half of these patients are expected to survive with current therapies. The combination of temozolomide and...