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Article
Open AccessThe impact of integrated disease management in high-risk COPD patients in primary care
Patients with chronic obstructive pulmonary disease (COPD) have a reduced quality of life (QoL) and exacerbations that drive health service utilization (HSU). A majority of patients with COPD are managed in pr...
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Article
Assessment of function and quality of life in a phase II multi-institutional clinical trial of fractionated simultaneous in-field boost radiotherapy for patients with 1–3 metastases
We examined functional outcomes and quality of life of whole brain radiotherapy (WBRT) with integrated fractionated stereotactic radiotherapy boost (FSRT) for brain metastases treatment. Eighty seven people w...
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Article
Open AccessReducing treatment delay for early intervention: evaluation of a community based crisis helpline
A limited number of studies have assessed the pathways to care of patients experiencing psychosis for the first time. Helpline/clinic programs may offer patients who are still functional but have potential for...
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Article
Open AccessThe abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India
The outcome of first episode schizophrenia has several determinants. Socioecological factors, particularly living conditions, migration, community and culture, not only affect the level of risk but also the ou...
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Article
Medical Students’ Attitudes About Cosmetic Pesticides before and after an Ecosystem Health Seminar: A Pilot Study
The University of Western Ontario has incorporated ecosystem health as an integral component of its Community Health course for medical students. There is increasing concern regarding the negative health effec...
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Article
Level and direction of hope in cancer patients: an exploratory longitudinal study
Hope is an important factor to consider when caring for cancer patients as a key component of co** with adversity. The aim of our study was to address the following questions: Is there a difference in level ...
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Article
Radiotherapy for Pediatric Central Nervous System Tumors: A Regional Cancer Centre Experience
Introduction: The purpose of this review was to analyze outcomes for pediatric patients treated for more common (non-low grade glioma) primary central nervous system (CNS) tumors at a Reg...
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Article
Is the Health Utilities Index valid in total hip arthroplasty patients?
Purpose: The purpose of the study was to examine the construct validity of the Health Utilities Index Mark 2 (HUI2) and Mark 3 (HUI3) in patients with osteoarthritis (OA) needing total hip arthroplasty (THA). Ba...
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Article
High-dose continuous venous infusion of interleukin-2: Influence of dose and infusion rate on tumoricidal function and lymphocyte subsets
Previous clinical studies have demonstrated a dose-response relationship between enhancement of certain immune parameters and interleukin-2 (IL-2) dose in trials with low dosages of the cytokine. This has not ...