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  1. No Access

    Chapter

    Renal prostaglandins and leukotrienes

    Larry A. Walker, Jürgen C. Frölich in Reviews of Physiology, Biochemistry and Ph… (1987)

  2. No Access

    Article

    Synthesis and anticancer activities of fatty acid analogs of podophyllotoxin

    Derivatives of podophyllotoxin were prepared by coupling 10 FA with the C4-α-hydroxy function of podophyllotoxin. The coupling reactions between FA and podophyllotoxin were carried out by dicyclohexylcarbodiimide...

    Jamal Mustafa, Shabana I. Khan, Guoyi Ma, Larry A. Walker, Ikhlas A. Khan in Lipids (2004)

  3. No Access

    Article

    Synthesis, spectroscopic, and biological studies of novel estolides derived from anticancer active 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate

    Podophyllotoxin is a well-known natural antitumor agent with severe side effects, which led us to synthesize its numerous analogs in search of product(s) of improved therapeutic potential. Here, we report an e...

    Jamal Mustafa, Shabana I. Khan, Guoyi Ma, Larry A. Walker, Ikhlas A. Khan in Lipids (2004)

  4. No Access

    Article

    Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate

    4-O-Podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate (PHEFE) is a structurally novel FA analog of podophyllotoxin. In the present study, in vitro effects of PHEFE on a panel of 60 human tumor cell lines and its p...

    Guoyi Ma, Shabana I. Khan, Jamal Mustafa, Larry A. Walker, Ikhlas A. Khan in Lipids (2005)

  5. No Access

    Article

    Synthesis and in vitro cytotoxic activity of N-, F-, and S-ether derivatives of podophyllotoxin fatty acid adducts

    This paper represents the first synthesis, spectroscopic characterization, and antitumor evaluation of F-, N-, and S-containing C4α-FA derivatives of podophyllotoxin. In a synthetic strategy, a FA unit of 4-O-pod...

    Jamal Mustafa, Shabana I. Khan, Guoyi Ma, Larry A. Walker, Ikhlas A. Khan in Lipids (2005)

  6. No Access

    Article

    Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants

    l-Malate dehydrogenase (PfMDH) from Plasmodium falciparum, the causative agent for the most severe form of malaria, has shown remarkable similarities to l-lactate dehydrogenase (PfLDH). P...

    Anupam Pradhan, Prasenjit Mukherjee… in Molecular and Cellular Biochemistry (2009)

  7. No Access

    Article

    Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

    The present study was designed to evaluate the efficacy of wild yam root extract (WYRE) as a potential demethylating agent using two breast cancer cell lines, MCF-7 (estrogen receptor positive; ER+) and MDA-MB-23...

    Pranapda Aumsuwan, Shabana I. Khan… in In Vitro Cellular & Developmental Biology … (2015)