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  1. Article

    Author Correction: Architecture and dynamics of a desmosome–endoplasmic reticulum complex

    Navaneetha Krishnan Bharathan, William Giang, Coryn L. Hoffman in Nature Cell Biology (2024)

  2. No Access

    Article

    Architecture and dynamics of a desmosome–endoplasmic reticulum complex

    The endoplasmic reticulum (ER) forms a dynamic network that contacts other cellular membranes to regulate stress responses, calcium signalling and lipid transfer. Here, using high-resolution volume electron mi...

    Navaneetha Krishnan Bharathan, William Giang, Coryn L. Hoffman in Nature Cell Biology (2023)

  3. No Access

    Article

    Whole-cell organelle segmentation in volume electron microscopy

    Cells contain hundreds of organelles and macromolecular assemblies. Obtaining a complete understanding of their intricate organization requires the nanometre-level, three-dimensional reconstruction of whole ce...

    Larissa Heinrich, Davis Bennett, David Ackerman, Woohyun Park, John Bogovic in Nature (2021)

  4. No Access

    Article

    Automatic detection of synaptic partners in a whole-brain Drosophila electron microscopy data set

    We develop an automatic method for synaptic partner identification in insect brains and use it to predict synaptic partners in a whole-brain electron microscopy dataset of the fruit fly. The predictions can be...

    Julia Buhmann, Arlo Sheridan, Caroline Malin-Mayor, Philipp Schlegel in Nature Methods (2021)

  5. Chapter and Conference Paper

    Synaptic Cleft Segmentation in Non-isotropic Volume Electron Microscopy of the Complete Drosophila Brain

    Neural circuit reconstruction at single synapse resolution is increasingly recognized as crucially important to decipher the function of biological nervous systems. Volume electron microscopy in serial transmi...

    Larissa Heinrich, Jan Funke, Constantin Pape in Medical Image Computing and Computer Assis… (2018)

  6. Chapter and Conference Paper

    Deep Learning for Isotropic Super-Resolution from Non-isotropic 3D Electron Microscopy

    The most sophisticated existing methods to generate 3D isotropic super-resolution (SR) from non-isotropic electron microscopy (EM) are based on learned dictionaries. Unfortunately, none of the existing methods...

    Larissa Heinrich, John A. Bogovic in Medical Image Computing and Computer-Assis… (2017)