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    Article

    Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

    Unlike other nucleotide oligomerization domain-like receptors, Nlrp10 lacks a canonical leucine-rich repeat domain, suggesting that it is incapable of signal sensing and inflammasome formation. Here we show th...

    Dan** Zheng, Gayatree Mohapatra, Lara Kern, Yiming He in Nature Immunology (2023)

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    Article

    Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion

    Autophagy is a lysosomal degradation process involved in the turnover of organelles or other cell constituents, in providing sources for energy production under starving conditions and in cell metabolism. A ke...

    Lara Kern, Johanne Spreckels, Andrea Nist, Thorsten Stiewe in Cell and Tissue Research (2016)