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Article
Response of gut microbiota, antioxidation, and disease resistance to Pacific shrimp fed distiller’s dried grains with solubles replaced soybean meal
This experiment aimed to examine the potential of distiller’s dried grains with solubles (DDGS) meal as a substitute for soybean meal (SBM) in the Pacific shrimp diet. The study aimed to investigate how DDGS a...
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Article
Open AccessHaplotype-resolved genomes of two buckwheat crops provide insights into their contrasted rutin concentrations and reproductive systems
Two widely cultivated annual buckwheat crops, Fagopyrum esculentum and F. tataricum, differ from each other in both rutin concentration and reproductive system. However, the underlying genetic mechanisms remain p...
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Article
Open AccessA high-quality chromosome-level Eutrema salsugineum genome, an extremophile plant model
Eutrema salsugineum (2n = 14), a halophyte in the family Brassicaceae, is an attractive model to study abiotic stress tolerance in plants. Two versions of E. salsugineum genomes that previously reported were base...
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Article
Open AccessTranscriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii)
Maintaining osmotic equilibrium plays an important role in the survival of cold-water fishes. Heat stress has been proven to reduce the activity of Na+/K+-ATPase in the gill tissue, leading to destruction of the ...
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Article
Regulative effect of imazethapyr on Arabidopsis thaliana growth and rhizosphere microbial community through multiple generations of culture
Imazethapyr (IM) is a chiral herbicide with two enantiomers, with a much stronger herbicidal effect of R-IM than S-IM. Pesticide residues are a common problem, and multi-generation cultivation method can reveal t...
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Article
Open AccessInhibition of long non-coding RNA XIST upregulates microRNA-149-3p to repress ovarian cancer cell progression
Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play critical roles in human diseases. We aimed to clarify the role of lncRNA X-inactive specific transcript (XIST)/miR-149-3p/forkhead box P3 (FOXP3) axis...
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Article
Evolutionary insights into the active-site structures of the metallo-β-lactamase superfamily from a classification study with support vector machine
The metallo-β-lactamase (MβL) superfamily, which is intriguing due to its enzyme promiscuity, is a good model enzyme superfamily for studies of catalytic function evolution. Our previous study traced the evolu...
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Article
Open AccessFBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1
Heat shot protein 90 (HSP90) AA1 functions as an onco-protein to regulate the assembly, manipulation, folding and degradation of its client proteins, including c-MYC. However, little is known about the mechani...
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Article
Express sequence tag analysis – Identification of anseriformes trypsin genes from full-length cDNA library of the duck (Anas platyrhynchos) and characterization of their structure and function
Trypsins are key proteins important in animal protein digestion by breaking down the peptide bonds on the carboxyl side of lysine and arginine residues, hence it has been used widely in various biotechnologica...
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Article
Simultaneous Determination of Calycosin-7-O-β-d-Glucoside, Ononin, Calycosin, Formononetin, Astragaloside IV, and Astragaloside II in Rat Plasma After Oral Administration of Radix Astragali Extraction for Their Pharmacokinetic Studies by Ultra-Pressure Liquid Chromatography with Tandem Mass Spectrometry
A sensitive and reliable ultra-pressure liquid chromatography with tandem mass spectrometry (UPLC–MS) was developed and validated for simultaneous quantification of six main bioactive components, i.e., calycos...
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Article
Effect of Sulfate Availability on the Isotopic Signature of Reduced Sulfurous Compounds in the Sediments of a Subtropical Estuary
We examined spatial patterns of sulfate utility and δ 34S signatures of sulfur species in sediments of a northern Taiwan subtropical estuary in December 2007. Results distinguished a sulfide-conce...
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Article
K-Ras and mitochondria: Dangerous liaisons
It is well documented that the K-RAS oncogene efficiently transforms non-malignant cells, and there is some evidence for the role of mitochondria in this process. Now Peng Huang and colleagues show that K-Ras ind...
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Article
Diversity and Composition of Sulfate- and Sulfite-Reducing Prokaryotes as Affected by Marine-Freshwater Gradient and Sulfate Availability
Sulfate- and sulfite-reducing prokaryotes (SSRP) communities play a key role in both sulfur and carbon cycles. In estuarine ecosystems, sulfate concentrations change with tides and could be limited in tidal fr...
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Article
Synergistic effect of ethylene inhibitors and putrescine on shoot regeneration from hypocotyl explants of Chinese radish (Raphanus sativus L. var. longipinnatus Bailey) in vitro
The role of ethylene and putrescine on shoot regeneration from hypocotyl explants of Chinese radish (Raphanus sativus L. var. longipinnatus Bailey cv. Red Coat) was investigated. Explants were recalcitrant in cul...
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Article
Insect resistance of transgenic plants that express modified Bacillus thuringiensis cryIA(b) and cryIC genes: a resistance management strategy
Tobacco and tomato plants were generated exhibiting insect resistance due to the introduction of modified cryIA(b) and cryIC genes of Bacillus thuringiensis. Limited modifications at selected regions of the codin...