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Article
Infection control interventions affected by resource shortages: impact on the incidence of bacteremias caused by carbapenem-resistant pathogens
We evaluated an infection control (IC) program influenced by personnel and material resource shortages on the incidence of bloodstream infections (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP), Ac...
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Article
Managing turbinate hypertrophy: coblation vs. radiofrequency treatment
The role of inferior turbinate hypertrophy in the reduction of nasal airflow is well established. Although chronic nasal obstruction is not life- threatening, it significantly impairs patients’ quality of life...
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Article
Tau Protein Detection in Anosmic Alzheimer’s Disease Patient’s Nasal Secretions
In the recent years, olfactory disorders are described in a wide range of neurological disorders such as Alzheimer’s disease. Neurofibrillary tangles, one of the hallmark pathologic indicators of Alzheimer’s d...
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Article
The endocrine disruptor cadmium alters human osteoblast-like Saos-2 cells homeostasis in vitro by alteration of Wnt/β-catenin pathway and activation of caspases
The pollutant Cadmium (Cd) is widespread in the environment and causes alterations of human health by acting as an endocrine disruptor. Bone tissue seems to be a crucial target of Cd contamination. Indeed, we ...
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Article
Open AccessMuscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation
Mitochondrial fission and fusion are essential processes in the maintenance of the skeletal muscle function. The contribution of these processes to muscle development has not been properly investigated in vivo be...
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Article
Cadmium-induced apoptosis and necrosis in human osteoblasts: Role of caspases and mitogen-activated protein kinases pathways
Cadmium is a widespread environmental pollutant which induces severe toxic alterations, including osteomalacia and osteoporosis, likely by estrogen receptor-dependent mechanisms. Indeed, cadmium has been descr...
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Chapter
Lanthionine Decarboxylation by Animal Tissues
Taurine content in animal tissues, ranging from 1 to 38 μmoles/g of wet tissue(1), exceeds 5–200 fold the cellular concentration of each aminoacid. The metabolic pathways leading to taurine are summarized in f...
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Article
Chemical modifications of histidine residues in cytoplasmic asparate aminotransferase from beef kidney
Holo and apoenzyme of aspartate aminotransferase from beef kidney are 80% inactivated by photoxidation in the presence of 2 × 10−6 m tetraiodofluroescein with the modification of two histidine residues per enzyme...
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Article
Role of tyrosine residues in cytoplasmic aspartate aminotransferase from beef kidney
Cytoplasmic aspartate aminotransferase from beef kindney loses 25% of its activity on nitration with tetranitromethane while the apoenzyme about 95%. In the holoenzyme 0.5 tyrosine residue and 1.0 tyrosine res...
