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Article
Open AccessImpact of solitary pulmonary nodule size on qualitative and quantitative assessment using 18F-fluorodeoxyglucose PET/CT: the SPUTNIK trial
To compare qualitative and semi-quantitative PET/CT criteria, and the impact of nodule size on the diagnosis of solitary pulmonary nodules in a prospective multicentre trial.
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Article
The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress
The family of ADAM (a disintegrin and metalloproteinase) proteins has been implicated in tumor initiation and progression. ADAM17/tumor necrosis factor-α (TNFα)-converting enzyme (TACE) has been initially reco...
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Article
Regulation of autophagy by ATF4 in response to severe hypoxia
Activating transcription factor 4 (ATF4) is a transcription factor induced under severe hypoxia and a component of the PERK pathway involved in the unfolded protein response (UPR), a process that protects cell...
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Chapter and Conference Paper
In-vivo red fluorescent protein tomography
We report on a novel mutli-spectral tomographic method that allows the 3D visualization of fluorescence protein activity in small animals. The method makes use of a novel spectral inversion scheme that integra...