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Article
Open AccessGene expression profile in functioning and non-functioning nodules of autonomous multinodular goiter from an area of iodine deficiency: unexpected common characteristics between the two entities
Toxic multinodular goiter is a heterogeneous disease associated with hyperthyroidism frequently detected in areas with deficient iodine intake, and functioning and non-functioning nodules, characterized by inc...
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Article
Frequency and effect on serum TSH of phosphodiesterase 8B (PDE8B) gene polymorphisms in patients with sporadic nonautoimmune subclinical hypothyroidism
Nonautoimmune subclinical hypothyroidism (NSH) is characterized by elevated serum TSH in presence of normal thyroid hormone levels and absence of anti-thyroid antibodies. As result of a genomic-wide study, a s...
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Article
Thyroglobulin autoantibodies of patients with subacute thyroiditis are restricted to a major B cell epitope
Background: Thyroglobulin autoantibodies (TgAb) can develop in patients with subacute thyroiditis (SAT). Aim: Comparison of the epitope pattern of TgAb of patients with SAT, Hashimoto’s thyroiditis (HT) [autoimm...
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Article
TSH receptor and Gsα genetic analysis in children with Down’s syndrome and subclinical hypothyroidism
The prevalence of thyroid diseases in children with Down’s syndrome (DS) is about 3%. The most frequently observed condition is autoimmune subclinical hypothyroidism (SH). Autoimmune SH must be distinguished f...
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Article
Chronic recurrent stress due to panic disorder does not precipitate Graves’ disease
A role of psychic stress in precipitating hyperthyroid Graves’ disease has been suggested, but the evidence in support of this pathogenetic mechanism is conflicting. In this study we investigated the possible ...
