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    Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

    Huntington's disease is an autosomal-dominant progressive neurodegenerative disorder resulting in specific neuronal loss and dysfunction in the striatum and cortex1. The disease is universally fatal, with a mean ...

    Victor O. Ona, Mingwei Li, Jean Paul G. Vonsattel, L. John Andrews… in Nature (1999)