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  1. Article

    Open Access

    A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis

    Linezolid is an effective, but toxic anti-tuberculosis drug that is currently recommended for the treatment of drug-resistant tuberculosis. Improved oxazolidinones should have a better safety profile, while pr...

    A Dierig, M Hoelscher, S Schultz, L Hoffmann, A Jarchow-MacDonald, EM Svensson in Trials (2023)

  2. Article

    Open Access

    Patients’ perceptions on temporomandibular disorder treatment with hydrostatic oral splints - a pilot study

    To evaluate temporomandibular disorder (TMD) treatment with a prefabricated, hydrostatic oral splint (HOS) based on self-reported patient’s symptoms using a standardized questionnaire.

    H. Sabbagh, A. Sabbagh, A. Heppner, C. Auer, A. Wichelhaus, L. Hoffmann in BDJ Open (2022)

  3. No Access

    Chapter

    Attitude Control on GRACE Follow-On: Experiences from the First Years in Orbit

    The two satellites for the GRACE (Gravity Recovery And Climate Experiment) Follow-On mission were successfully launched in May 2018 into a polar orbit at an altitude of 491 km. Its predecessor GRACE was operat...

    F. Cossavella, J. Herman, L. Hoffmann, D. Fischer, H. Save, B. Schlepp in Space Operations (2022)

  4. Article

    Open Access

    From Ultraslow to Extremely Fast Dynamics in Sodium Nitrate: an 17O NMR Study

    Increasing dynamics in solids featuring nuclei subjected to second-order quadrupolar interactions lead to central-transition spectra that undergo two consecutive line-shaped transitions. Conventional motional ...

    J. Beerwerth, R. Siegel, L. Hoffmann, L. S. Plaga, M. Storek in Applied Magnetic Resonance (2020)

  5. Article

    Open Access

    Suppressed decomposition of organometal halide perovskites by impermeable electron-extraction layers in inverted solar cells

    The area of thin-film photovoltaics has been overwhelmed by organometal halide perovskites. Unfortunately, serious stability concerns arise with perovskite solar cells. For example, methyl-ammonium lead iodide...

    K.O. Brinkmann, J. Zhao, N. Pourdavoud, T. Becker, T. Hu in Nature Communications (2017)

  6. Article

    Topic: Femoral Hernia — Complications

    S. Axer, H. Lederhuber, B. Hansske, L. Hoffmann in Hernia (2015)

  7. No Access

    Article

    Prevalence of paternal perinatal depressiveness and its link to partnership satisfaction and birth concerns

    Depressive disorders have shown an increasing prevalence over the past decades. Growing evidence suggests that pregnancy and childbirth trigger depressive symptoms not only in women but likewise in men. This s...

    S. Gawlik, M. Müller, L. Hoffmann, A. Dienes in Archives of Women's Mental Health (2014)

  8. No Access

    Article

    Limited mitochondrial DNA diversity is indicative of a small number of founders of the German raccoon (Procyon lotor) population

    The raccoon (Procyon lotor) has successfully invaded central Europe, despite the population apparently having been founded by a small number of individuals in two distinct populations in Germany. The ecological s...

    A. C. Frantz, M. Heddergott, J. Lang, C. Schulze in European Journal of Wildlife Research (2013)

  9. No Access

    Article

    ENSEMBLES-based assessment of regional climate effects in Luxembourg and their impact on vegetation

    Projected future regional climate changes in Luxembourg are assessed based on a six-member ensemble of regional climate models (RCM) from the ENSEMBLES project. The key aspects are projected changes in air tem...

    K. Goergen, J. Beersma, L. Hoffmann, J. Junk in Climatic Change (2013)

  10. No Access

    Article

    Towards a synthetic view of potato cold and salt stress response by transcriptomic and proteomic analyses

    Potato can suffer from several abiotic stresses such as cold temperature, high soil salinity, lack of water or heavy metal exposure, to name a few. They are known to affect plant growth as well as productivity...

    D. Evers, S. Legay, D. Lamoureux, J. F. Hausman, L. Hoffmann in Plant Molecular Biology (2012)

  11. No Access

    Chapter and Conference Paper

    Farm animal proteomics in toxicological studies: useful tool or waste of time? what to learn from rodent studies

    In recent years sheep (Oviesaries) and goats (Capra aegagrushircus) have been increasingly used as model animals in toxicology and a plethora of effects due to exposure with polyhalogenated aromatic hydrocarbons ...

    T. Serchi, I. Miller, E. Rijntjes, J. Renaut, A. J. Murk in Farm animal proteomics (2012)

  12. Article

    Relevanz von Feinpartikeln in Hydrologie und Wasserwirtschaft: Herkunft, Transport, Wirkung und Management in natürlichen und technischen Systemen

    A. Kurtenbach, R. Bierl, B. Eisold in Umweltwissenschaften und Schadstoff-Forsch… (2010)

  13. No Access

    Article

    Spatio-temporal variability of behavioral patterns in hydrology in meso-scale basins of the Rhineland Palatinate (1972–2002)

    Changes in spatio-temporal rainfall patterns have an effect on the hydrological behavior of river basins, the magnitude of the effects depending among others on the physiographic basin characteristics. To asse...

    H. Hellebrand, R. van den Bos, L. Hoffmann, J. Juilleret, A. Krein in Climatic Change (2009)

  14. No Access

    Article

    Imaging Chemical Patches on Near-surface Atmospheric Dust Particles with NanoSIMS 50 to Identify Material Sources

    The increase of traffic and the rising energy consumption mean a challenge to the air pollution control and to environmental protection. Measures of air pollution control concentrated primarily on the reductio...

    A. Krein, T. Udelhoven, J.-N. Audinot, C. Hissler in Water, Air, & Soil Pollution: Focus (2008)

  15. No Access

    Chapter and Conference Paper

    Impact of Do** Density in Short-Wavelength InP-Based Strain-Compensated Quantum-Cascade Lasers

    The authors present the effect of injector do** concentrations between 0.7 × 1016 cm−3 and 3.9 × 1017 cm−3 on the performance of short-wavelength InP-based quantum-cascades lasers (QCL) emitting around 3.8 μm. ...

    E. Mujagić, M. Austerer, S. Schartner, M. Nobile in Narrow Gap Semiconductors 2007 (2008)

  16. No Access

    Article

    Vertically Increasing Well Thickness and In Content in GaInN MQW’s due to V-shaped Pits

    In this work we investigate the influence of V-shaped pits on the growth of GaInN-GaN MQW’s by TEM and x-ray diffraction measurements. We have grown different MQW’s using low-pressure MOVPE and studied the inf...

    H. Bremers, L. Hoffmann, D. Fuhrmann, U. Rossow in MRS Online Proceedings Library (2007)

  17. No Access

    Article

    A late blight resistant potato plant overexpresses a gene coding for α-galactosidase upon infection by Phytophthora infestans

    Late blight of potato, caused by Phytophthora infestans was studied by using a resistant clone of potato on one side and a susceptible clone on the other side. A gene coding putatively for an α-galactosidase has ...

    D. Evers, M. Ghislain, L. Hoffmann, J. F. Hausman, J. Dommes in Biologia Plantarum (2006)

  18. No Access

    Article

    Recent warming in a small region with semi-oceanic climate, 1949–1998: what is the ground truth?

    Trends of monthly air temperature extremes were investigated in five meteorological stations of the Grand-Duchy of Luxembourg during the period 1949–1998. The application of an innovative homogenization method...

    G. Drogue, O. Mestre, L. Hoffmann, J.-F. Iffly in Theoretical and Applied Climatology (2005)

  19. No Access

    Chapter

    Prediction with artificial neural networks of diatom assemblages in headwater streams of Luxembourg

    F Rimet, L Ector, L Hoffmann, M Gevrey in Modelling Community Structure in Freshwate… (2005)

  20. No Access

    Article

    Assessing land use impacts on flood processes in complex terrain by using GIS and modeling approach

    A distributed hydrologic modeling and GIS approach is applied for the assessment of land use impact in the Steinsel sub-basin, Alzette, Grand-Duchy of Luxembourg. The assessment focuses on the runoff contribut...

    Y. B. Liu, F. De Smedt, L. Hoffmann, L. Pfister in Environmental Modeling & Assessment (2005)

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