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The non-steroidal anti-inflammatory drug salsalate provides safe and effective control of mucositis-unrelated pain during autologous and allogeneic hematopoietic stem cell transplantation
Pain is a serious adverse event which frequently accompanies hematopoietic stem cell transplantation (HSCT). The safety and efficacy of NSAIDS during HSCT is currently unknown. Salsalate is a platelet-sparing ...
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Article
Correction to: Exercise following breast cancer: exploratory survival analyses of two randomised, controlled trials
In the original publication of the article, under the heading Discussion, 1st paragraph, the sentence that reads as, “Nonetheless, our observed improvements of over 50% for OS and over 30% for DFS (HRs: 0.45 a...
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Exercise following breast cancer: exploratory survival analyses of two randomised, controlled trials
The Exercise for Health trials were randomised, controlled trials designed to evaluate an 8-month pragmatic exercise intervention, commencing 6 weeks post-surgery for women with newly diagnosed breast cancer r...
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Open AccessWhole exome sequencing in systemic juvenile idiopathic arthritis
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Attenuation of ischemia-reperfusion injury in swine resuscitated for hemorrhagic shock by low-dose inhaled nitrite or carbon monoxide
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Open AccessInhaled carbon monoxide or nebulized sodium nitrite protect against hemorrhagic shock-induced mitochondrial dysfunction
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Open AccessCLARITY: C hiL dhood A rthritis R isk Factor I dentification ST udY. Investigating the role of aberrant DNA methylation in juvenile idiopathic arthritis
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Actual or ideal body weight to calculate CD34+ cell dose in patients undergoing autologous hematopoietic SCT for myeloma?
CD34+ cell dose calculations are usually based on actual body weight (ABW). We have shown that ideal body weight (IBW) may provide a better basis for this in a small population of patients with hematologic mal...
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Article
RASSF6 is a novel member of the RASSF family of tumor suppressors
RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. The best-characterized member of the family is RASSF1A, which is downregulated by promoter ...
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Breakthrough fungal infections after allogeneic hematopoietic stem cell transplantation in patients on prophylactic voriconazole
Seventy-one allograft recipients receiving voriconazole, in whom complete clinical, microbiologic and pharmacokinetic data were available, were studied to determine the efficacy of voriconazole in preventing f...
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Reduced-dose rasburicase (recombinant xanthine oxidase) in adult cancer patients with hyperuricemia
Recombinant urate oxidase (rasburicase) lowers uric acid levels rapidly to very low levels at the labeled dose of 0.15–0.2 mg/kg daily for 5 days. Our past experience showed that a lower dose (3 mg) lowered ur...
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Can the stem cell mobilization technique influence CD34+ cell collection efficiency of leukapheresis procedures in patients with hematologic malignancies?
A total of 415 leukaphereses in 201 patients stimulated with growth factor (GF; n=119) or chemotherapy-GF (n=296) were studied to determine CD34+ cell collection efficiency (CE). The pre-apheresis leukocyte count...
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Abstracts of original contributions ASNC 2004 9th annual scientific session September 3-–October 3, 2004 New York, New York
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How long after neutrophil recovery should myeloid growth factors be continued in autologous hematopoietic stem cell transplant recipients?
Growth factors are routinely used after autotransplantation to accelerate hematopoietic recovery, and are continued until the absolute neutrophil count (ANC) is ⩾0.5 × 109/l on 3 consecutive days. Since ANC often...
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Factors associated with survival in patients with progressive disease following autologous transplant for lymphoma
Our objectives were to assess survival and predictors for survival among lymphoma patients whose disease had progressed after autologous bone marrow (ABMT) or stem cell transplantation (ASCT). Patients transpl...
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Rarity of toxigenic Clostridium difficile infections after hematopoietic stem cell transplantation: implications for symptomatic management of diarrhea
Diarrhea is a common complication of high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT). The frequent and prolonged use of multiple antibiotics in this setting can predispose to infectio...
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Cobe Spectra is superior to Fenwal CS 3000 Plus for collection of hematopoietic stem cells
One hundred and seventy-seven stem cell apheresis procedures performed on 91 patients using the Fenwal CS 3000 Plus cell separator and 61 procedures performed on 37 patients using the Cobe Spectra cell separat...
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CD34+ cell collection efficiency does not correlate with the pre-leukapheresis hematocrit
One hundred and seventy-seven large-volume leukapheresis procedures performed on 91 patients over a 15 month period were reviewed to see if the pre-apheresis hematocrit (Hct) affected the CD34+ cell collection ef...
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Delayed laparoscopy facilitates the management of biliary peritonitis in patients with complex liver injuries
Nonoperative management is now regarded as the best alternative for the treatment of patients with complex blunt liver injuries. However, some patients still require surgical treatment for complications that w...
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Structural and functional changes in root cells induced by calcium ionophore A23187
The shifts of Ca2+, K+ and proton homeostasis of wheat (Triticum aestivum L. M. cv Ljuba) root cells induced by the Ca2+-ionophore A23187 caused different responses, depending on the time of exposure to the ionop...