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Article
Open AccessLaparoscopic transhiatal suture and gastric valve as a safe and feasible treatment for Boerhaave’s syndrome: an Italian single center case series study
Boerhaave’s syndrome (BS) is a rare life-threating condition with poor prognosis. Unfortunately, due to its very low incidence, no clear evidences or definitive guidelines are currently available: in detail, s...
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Article
Perianastomotic drainage in Ivor-Lewis esophagectomy, does habit affect utility? An 11-year single-center experience
Anastomotic leakage (AL) is a deadly complication after Ivor-Lewis esophagectomy. The use of an anastomotic drainage (AD), to diagnose and to potentially treat the leakage, is still a widespread practice. At p...
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Article
Recent Innovations & Daily Problems
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Article
Open AccessMutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3)
Huntington's disease (HD) is a neurodegenerative disorder characterized by progressive neuronal death in the basal ganglia and cortex. Although increasing evidence supports a pivotal role of mitochondrial dysf...
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Article
Type 2 diabetes and metabolic syndrome are associated with increased expression of 11β-hydroxysteroid dehydrogenase 1 in obese subjects
The role of glucocorticoids production in adipose tissue in the development of metabolic disorders in humans has not been fully characterized. We investigated whether in obese subjects, 11β-hydroxysteroid dehydro...
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Article
SH2B1β adaptor is a key enhancer of RET tyrosine kinase signaling
The RET gene encodes two main isoforms of a receptor tyrosine kinase (RTK) implicated in various human diseases. Activating germ-line point mutations are responsible for multiple endocrine neoplasia type 2-associ...
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Article
Thérapeutiques moléculaires ciblées des sarcomes des tissus mous: actualités et perspectives
Les sarcomes constituent un groupe hétérogène de tumeurs malignes développées aux dépens des cellules composant les tissus de soutien spécialisés et non spécialisés. Les progrès accomplis dans la compréhension...
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Article
Increased apoptosis, huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects
Mutated huntingtin (htt) is ubiquitously expressed in tissues of Huntington's disease (HD) patients. In the brain, the mutated protein leads to neuronal cell dysfunction and death, associated with formation of...
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Article
Psychoonkologische Aspekte im Rahmen der genetischen Beratung von Hochrisikofamilien
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Article
The relationship of plasma glucose and electrocardiographic parameters in elderly women with different degrees of glucose tolerance
Plasma glucose has been regarded as a risk factor for macrovascular complications in diabetes, but less is known about its role in the development of cardiac impairment other than coronary heart disease (CHD)....
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Article
Diagnosing mental disorders in primary care: the General Health Questionnaire (GHQ) and the Symptom Check List (SCL-90-R) as screening instruments
Background: The treatment of mental disorders in Germany is mainly done by primary care physicians. Several studies have shown that primary care physicians have difficulty in diagnosing ...
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Article
A kit of human polyclonal IgG for the diagnosis of infectious processes
The aim of this work was to obtain a freeze-dried kit for direct99mTc-labeling of human polyclonal IgG. The labeling procedure was carried out by Schwarz's method. The best yields of99mTc-IgG were obtained by usi...
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Article
Grb2 binding to the different isoforms of Ret tyrosine kinase
The RET proto-oncogene encodes two isoforms of a receptor tyrosine kinase which plays a role in neural crest and kidney development. Ret ligands have been recently identified as the neuron survival factor GDNF...
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Article
Psychosomatische Störungen in der Dermatologie – Häufigkeiten und psychosomatischer Mitbehandlungsbedarf
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Article
A numerical simulation of the transport of surface ozone along a Mediterranean coastal area
A simple numerical simulation of daily summer circulation in W-NW and E-SE directions was applied to a coastal area of Greater Ravenna in Northern Italy to assess the influence on ozone levels of the transport...
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Chapter
Erarbeiten von Behandlungsregeln — Standards zum Auffinden und Behandeln der Hypertonie. Ein Modellversuch zur Qualitätssicherung in der ambulanten Versorgung
Das Projekt patientenbezogene Verordnungsverläufe (FW) will einen Beitrag zur Qualitätssicherung und Beurteilung der Arzneitherapie der Patienten niedergelassener Ärzte liefern. Der Erarbeitung von Regeln bzw....
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Chapter and Conference Paper
Wie kann Balint-Gruppenarbeit angemessen mit empirischen Forschungsansätzen untersucht werden?
Eine Abneigung gegenüber empirischer Forschung ist nicht alleine in der Balint-Gruppenarbeit zu beobachten. In der Psychotherapie im allgemeinen ist eine solche Abneigung zu spüren, obwohl wir inzwischen in de...
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Chapter and Conference Paper
Empirischer Vergleich zur Leitungstechnik — Wieviel sprechen Leiter und Teilnehmer in Selbsterfahrungs- und Balint-Gruppen?
Michael Balint (1957) wies früh auf die Notwendigkeit vergleichender empirischer Untersuchungen von Balint- und therapeutischen Gruppen hin. Er gehörte zu den Pionieren der Londoner Tavistock-Klinik, in der zu...
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Article
Impact of decisive changes in the clinical milieu on chronic psychiatric inpatients
With the help of the Nurses' Observation Scale for Inpatient Evaluation, the effect of stress was examined in 79 middle-aged and elderly, predominantly schizophrenic patients who were chronically ill, and had ...
