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  1. No Access

    Article

    Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice

    PU.1 downregulation within hematopoietic stem and progenitor cells (HSPCs) is the primary mechanism for the development of acute myeloid leukemia (AML) in mice with homozygous deletion of the upstream regulato...

    P Basova, V Pospisil, F Savvulidi, P Burda, K Vargova, L Stanek, M Dluhosova… in Oncogene (2014)

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    Article

    Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

    Brain-derived neurotrophic factor (BDNF) is known to play a critical role in the synaptic plasticity underlying the acquisition and/or consolidation of certain forms of memory. Additionally, a role has been su...

    S A Heldt, L Stanek, J P Chhatwal, K J Ressler in Molecular Psychiatry (2007)