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  1. No Access

    Article

    RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia

    Acute myeloid leukemia (AML) with the FLT3 internal tandem duplication (FLT3-ITD AML) accounts for 20–30% of AML cases. This subtype usually responds poorly to conventional therapies, and might become resistant t...

    M-A Hospital, A Jacquel, F Mazed, E Saland, C Larrue, J Mondesir, R Birsen… in Leukemia (2018)

  2. Article

    Open Access

    Measurements of PM10 ions and trace gases with the online system MARGA at the research station Melpitz in Germany – A five-year study

    An hourly quantification of inorganic water-soluble PM10 ions and corresponding trace gases was performed using the Monitor for AeRosols and Gases in ambient Air (MARGA) at the TROPOS research site in Melpitz, Ge...

    B. Stieger, G. Spindler, B. Fahlbusch, K. Müller… in Journal of Atmospheric Chemistry (2018)

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  3. Article

    Open Access

    Novel insights on new particle formation derived from a pan-european observing system

    The formation of new atmospheric particles involves an initial step forming stable clusters less than a nanometre in size (<~1 nm), followed by growth into quasi-stable aerosol particles a few nanometres (~1–1...

    M. Dall’Osto, D. C. S. Beddows, A. Asmi, L. Poulain, L. Hao… in Scientific Reports (2018)

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  4. No Access

    Chapter and Conference Paper

    Kinetic Modeling of SOA Formation for \(\alpha \) - and \(\beta \) -Pinene

    In the last years, two major findings concerning secondary organic aerosol (SOA) were reported. Firstly, the aerosol particles formed by the organic compounds are higher viscous than previously thought. Up to ...

    K. Gatzsche, Y. Iinuma, A. Mutzel, T. Berndt… in Air Pollution Modeling and its Application… (2018)

  5. No Access

    Article

    High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

    Alterations in metabolic activities are cancer hallmarks that offer a wide range of new therapeutic opportunities. Here we decipher the interplay between mTORC1 activity and glucose metabolism in acute myeloid...

    L Poulain, P Sujobert, F Zylbersztejn, S Barreau, L Stuani, M Lambert… in Leukemia (2017)

  6. No Access

    Article

    Photocatalytic abatement results from a model street canyon

    During the European Life+ project PhotoPAQ (Demonstration of Photocatalytic remediation Processes on Air Quality), photocatalytic remediation of nitrogen oxides (NOx), ozone (O3), volatile organic compounds (VOCs...

    M. Gallus, R. Ciuraru, F. Mothes, V. Akylas… in Environmental Science and Pollution Resear… (2015)

  7. Article

    Open Access

    miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation

    We sought to identify miRNAs that can efficiently induce apoptosis in ovarian cancer cells by overcoming BCL-XL and MCL1 anti-apoptotic activity, using combined computational and experimental approaches. We found...

    C Denoyelle, B Lambert, M Meryet-Figuière, N Vigneron, E Brotin… in Cell Death & Disease (2014)

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  8. No Access

    Article

    Reportages Photographiques

    X. Grapton, P. Khalifa, D. Leclere, P. Lemesle, L. Poulain… in Médecine et Chirurgie du Pied (2014)

  9. No Access

    Article

    Intraperitoneal linear polyethylenimine (L-PEI)-mediated gene delivery to ovarian carcinoma nodes in mice

    Linear polyethylenimine (L-PEI) is an efficient transfection agent for ovarian carcinoma cells in vitro and ex vivo. In the present work, we go a step further and evaluate the efficacy of L-PEI in human ovarian t...

    M-H Louis, S Dutoit, Y Denoux, P Erbacher, E Deslandes, J-P Behr… in Cancer Gene Therapy (2006)