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Article
Structural characterization of rhamnogalacturonan-I purified from Curcuma longa and its anti-lung cancer efficacy via immunostimulation
In this study, we investigated the structural characteristics, immunostimulatory activities, and anti-cancer effects of turmeric-derived polysaccharides (TPE-I). Several results related to the structural featu...
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Article
Identification of intracellular activation mechanism of rhamnogalacturonan-I type polysaccharide purified from Panax ginseng leaves in macrophages and roles of component sugar chains on activity
This study aimed to investigate the mechanisms underlying intracellular signaling pathways in macrophages in relation to the structural features of rhamnogalacturonan (RG) I-type polysaccharide (PGEP-I) purifi...
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Article
Synergistic effect of Korean red ginseng extract and GABA mixture on the IgE production in mice via Th1/Th2 cell balance
It has been recently reported that the immune system has been linked to the nervous system. This study was conducted to investigate the effect of administration of two components, gamma-aminobutyric acid (GABA...
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Article
Anti-asthma and antitussive effects of a fermented extract of a mixture of Ramulus mori, Anthriscus sylvestris, and Salvia plebeian
Respiratory immunity is getting more important recently due to outbreak of respiratory diseases and increasing the concentration of fine dust. The aim of this study was to investigate respiratory protection ef...
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Article
Characterization of new oligosaccharide converted from cellobiose by novel strain of Bacillus subtilis
Six bacterial strains isolated from various Korean fermented foods were cultured in cellobiose-containing medium to investigate their potential for producing new kind of oligosaccharides. After bacterial cultu...
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Article
In vitro and in vivo effects of polysaccharides isolated from Korean persimmon vinegar on intestinal immunity
The in vitro and in vivo effects of crude polysaccharide isolated from Korean persimmon vinegar (KPV-0) on the intestinal immunostimulation were examined. KPV-0 was not cytotoxic to intestinal epithelial Caco-...
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Article
Prebiotic effects of structurally identified galacto-oligosaccharides produced by β-galactosidase from Aspergillus oryzae
Novel galacto-oligosaccharides were produced by β-galactosidase from Aspergillus oryzae using lactose, and their structural characteristics and prebiotic effects were examined. Highly purified oligosaccharide fra...
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Article
Photoprotective Effects of a Formulation Containing Tannase-Converted Green Tea Extract Against UVB-Induced Oxidative Stress in Hairless Mice
Ultraviolet B (UVB) irradiation may induce the acceleration of skin aging. The purpose of this study was to develop an effective formulation containing tannase-converted green tea extract (FTGE) to inhibit UVB...
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Article
Transformation of ginsenoside-rich fraction isolated from ginseng (Panax ginseng) leaves induces compound K
To develop the new physiologically active materials from ginseng (Panax ginseng C.A. Meyer) leaves, the ginsenoside-rich fraction (GL-1) was isolated and transformed into highly absorbable metabolites in the gast...
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Article
Fermentation of Korean Red Ginseng by Lactobacillus plantarum M-2 and Its Immunological Activities
We investigated ginsenoside transformation by fermentation of red ginseng with Lactobacillus plantarum M-2. We also examined the anti-metastasis and immune-stimulating activities of EtOH extracts of fermented red...
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Article
Isolation and characterization of immuno-stimulating polysaccharide in Korean black raspberry wine
To characterize polysaccharides existing as soluble form in Korean fruit wines, polysaccharides were isolated from Korean black raspberry wine, and their immuno-stimulating activities were examined. A complex ...
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Article
Determination of primary factors with adhesive property of Lactobacillus brevis FSB-1 to rat colonic mucin
To maintain the valid physiological effects of lactic acid bacteria LAB in large intestine, the adhesive properties of LAB to human colonic mucin HCM is essential. In this study, the primary factors associated...
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Article
Physiological activities of ginsenoside-rich fraction isolated from Panax ginseng leaves
In order to develop the new physiologically active materials from the leaves of Panax ginseng C.A. Meyer, the ginsenoside-rich fraction (GL-1) was isolated from ginseng leaves and physiological activities were ex...
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Article
Macrophage stimulating polysaccharide purified from peels of grape (Vitis labrusca)
To characterize the macrophage stimulating polysaccharide in grape (Vitis labrusca) peels, the active crude polysaccharide (VL-3) has been fractionated from the hot-water extract of grape peels. A macrophage stim...
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Article
Innate immune stimulation of exo-polymers prepared from Cordyceps sinensis by submerged culture
After we prepared exo-polymers (EPS) from Cordyceps sinensis by submerged culture, prophylactic intravenous administration (i.v.) of EPS significantly inhibited metastasis in experimental lung metastasis of colon...
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Article
Anti-Metastatic activity of glycoprotein fractionated fromacanthopanax senticosus, involvement of NK-cell and macrophage activation
Previously, we reported that water-extractedAcanthopanax senticosus exhibited anti-meta-static activity by stimulating the immune system. In this study, we fractionated glycoproteins (EN-SP) from the soluble prot...
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Article
Surface-displayed viral antigens on Salmonella carrier vaccine
We have developed a recombinant live oral vaccine using the ice-nucleation protein (Inp) from Pseudomonas syringae to display viral antigens on the surface of Salmonella spp. Fusion proteins containing viral anti...
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Article
Production of HBsAg by growth rate control with recombinantSaccharomyces cerevisiae in fed-batch
To maintain a constant specific growth rate for a recombinantS.cerevisiae in fed-batch, the medium feeding rate has been controlled with respect to the hourly calculated glucose uptake rate. The recombinant yeast...
