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Open AccessGroup I pharmaceuticals of IARC and associated cancer risks: systematic review and meta-analysis
We aimed to summarize the cancer risk among patients with indication of group I pharmaceuticals as stated in monographs presented by the International Agency for Research on Cancer working groups. Following th...
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Article
Isoflavone intake on the risk of overall breast cancer and molecular subtypes in women at high risk for hereditary breast cancer
We investigated the association between isoflavone (ISF) intake and hereditary breast cancer (BC) risk, particularly by molecular subtype, in East-Asian BRCA1/2 mutation carriers and non-carriers at a high risk o...
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Open AccessAssociations of urinary sodium levels with overweight and central obesity in a population with a sodium intake
Previous studies have reported an association between dietary sodium intake and overweight/central obesity. However, dietary survey methods were prone to underestimate sodium intake. Therefore, this study inve...
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The association between somatic and psychological discomfort and health-related quality of life according to the elderly and non-elderly
Symptoms and discomfort are common complaints in primary care settings. It has been postulated that the physical symptoms are informative index in estimating Health-related quality of life (HRQOL). Thus, we co...
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Formula for predicting OSA and the Apnea–Hypopnea Index in Koreans with suspected OSA using clinical, anthropometric, and cephalometric variables
This study developed formulas to predict obstructive sleep apnea (OSA) and the Apnea–Hypopnea Index (AHI) in Korean patients with suspected OSA using clinical, anthropometric, and cephalometric variables.
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Article
Perceived Social Support as a Determinant of Quality of Life Among Medical Students: 6-Month Follow-up Study
This longitudinal study aimed to identify the relevant factors related to quality of life (QoL) changes in medical students.
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Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Open AccessThe role of abnormal metabolic conditions on arterial stiffness in healthy subjects with no drug treatment
Subjects with abnormal metabolic conditions had increased risk for cardiovascular disease. We investigated the role of abnormal metabolic conditions on arterial stiffness in healthy subjects with no drug treat...
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Article
Open AccessImpact of alcohol drinking on gastric cancer development according to Helicobacter pylori infection status
Helicobacter pylori are major carcinogen of gastric cancer, but the associations among gastric cancer, H. pylori infection status, and alcohol consumption are not fully described. This study aimed to clarify how
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Article
Metformin intervention in obese non-diabetic patients with breast cancer: phase II randomized, double-blind, placebo-controlled trial
Previous observational studies have suggested that metformin in diabetes patients may reduce breast cancer risk more than the reductions from other anti-diabetes medications. This randomized, double-blind, pla...
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Article
Delayed diagnosis is linked to worse outcomes and unfavourable treatment responses in patients with axial spondyloarthritis
The diagnosis of spondyloarthritis (SpA) has a lengthy delay; we investigated the outcomes and factors associated with the delayed diagnosis of SpA. This was a cross-sectional study on patients with SpA who vi...
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Gene polymorphisms in the ornithine decarboxylase–polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations
The study aimed to examine the association between genes encoding molecules in the ornithine decarboxylase (ODC)–polyamine pathway (ODC1, AMD1, NQO1, NOS2A, and OAZ2) and gastric cancer risk and whether the gene–...
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Plasma isoflavone concentration is associated with decreased risk of type 2 diabetes in Korean women but not men: results from the Korean Genome and Epidemiology Study
To examine the association between soybean products and risk of type 2 diabetes, we measured four isoflavone biological markers—genistein, daidzein, glycitein and equol—in a nested case–control study.
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Open AccessIs radiotherapy necessary for intermediate risk ductal carcinoma in situ after breast conserving surgery?
Identifying ductal carcinoma in situ (DCIS) patients at highest risk for recurrence after breast conserving surgery (BCS) remains a clinical concern. Subjecting all such patients to radiotherapy may be unneces...
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Open AccessA flow visualization model of duodenogastric reflux after esophagectomy with gastric interposition
Our goal was to verify surgical factors that affect duodenogastric reflux (DGR) after esophagectomy through the use of a flow visualization model that would mimic an intrathoracic gastric tube.
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Open AccessRice-eating pattern and the risk of metabolic syndrome especially waist circumference in Korean Genome and Epidemiology Study (KoGES)
Metabolic syndrome poses a serious health threat in Asian countries. Rice is a staple food in Korea, and carbohydrate intake is associated with the risk of MetS. We hypothesized that various rice-eating patter...
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Epidemiological profiles between equol producers and nonproducers: a genomewide association study of the equol-producing phenotype
Equol is a daidzein (a phytoestrogen isoflavone) metabolite of gut bacteria, and the ability to produce equol varies between individuals and reduces the risks of several diseases. We tested the effects of equo...
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Ecological study for refrigerator use, salt, vegetable, and fruit intakes, and gastric cancer
We used an ecological approach to determine the correlation between vegetable, fruit and salt intakes, refrigerator use, and gastric cancer mortality in Korean population. Information on fruit and vegetable in...
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Open AccessThe role of TNFgenetic variants and the interaction with cigarette smoking for gastric cancer risk: a nested case-control study
The aim of this study was to investigate the role of TNF genetic variants and the combined effect between TNF gene and cigarette smoking in the development of gastric cancer in the Korean population.
