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  1. No Access

    Article

    Are dual-phase 18F-FDG PET scans necessary in nasopharyngeal carcinoma to assess the primary tumour and loco-regional nodes?

    This prospective study aimed to investigate the efficacy of dual-phase positron emission tomography (PET) in evaluating the loco-regional status of nasopharyngeal carcinoma (NPC).

    Tzu-Chen Yen, Yu-Chen Chang… in European Journal of Nuclear Medicine and M… (2005)

  2. No Access

    Article

    Improved accuracy of brain MRI/SPECT registration using a two-cluster SPECT normalization algorithm and a combinative similarity measure: application to the evaluation of Parkinson's disease

    Single-photon emission computed tomography (SPECT) of dopamine transporters with technetium-99-labeled tropane derivative 99mTc-TRODAT-1 has recently been suggested to offer valuable information in assessing the ...

    Jiann-Der Lee, Chung-Hsien Huang, Yi-Hsin Weng, Kun-Ju Lin… in Annals of Nuclear Medicine (2007)

  3. No Access

    Article

    Animal PET for Thioacetamide-Induced Rat Cholangiocarcinoma: A Novel and Reliable Platform

    Cholangiocarcinoma (CCA) is a lethal disease afflicting many thousands of patients worldwide. We have previously developed an oral thioacetamide (TAA)-induced model of rat CCA that recapitulates the histologic...

    Chun-Nan Yeh, Kun-Ju Lin, Ing-Tsung Hsiao, Tzu-Chen Yen… in Molecular Imaging and Biology (2008)

  4. No Access

    Article

    Fully Automatic Region of Interest Selection in Glomerular Filtration Rate Estimation from 99mTc-DTPA Renogram

    Glomerular filtration rate (GFR) is a common accepted standard estimation of renal function. Gamma camera-based methods for estimating renal uptake of 99mTc-diethylenetriaminepentaacetic acid (DTPA) without blood...

    Kun-Ju Lin, Jia-Yann Huang, Yung-Sheng Chen in Journal of Digital Imaging (2011)

  5. No Access

    Article

    In vivo imaging of radiation-induced tissue apoptosis by 99mTc(I)-his6-annexin A5

    A recombinant annexin A5 with the N-terminal extension of six histidine residues was labeled with 99mTc(I)-tricarbonyl ion to produce the 99mTc-labeled annexin A5, referred to 99mTc(I)-his6-annexin A5. We have ex...

    Kun-Ju Lin, Chun-Chung Wu, Yi-Hsin Pan, Fang-Hsing Chen… in Annals of Nuclear Medicine (2012)

  6. No Access

    Article

    Correlation of early-phase 18F-florbetapir (AV-45/Amyvid) PET images to FDG images: preliminary studies

    18F-Florbetapir (AV-45/Amyvid) is a novel positron emission tomography (PET) tracer for imaging plaque pathology in Alzheimer’s disease (AD), while PET images of fluorodeoxyglucose (FDG) for ce...

    Ing-Tsung Hsiao, Chin-Chang Huang… in European Journal of Nuclear Medicine and M… (2012)

  7. Article

    Correlation of early-phase 18F-florbetapir (AV-45/Amyvid) PET images to FDG images: preliminary studies: reply to Ballinger

    Ing-Tsung Hsiao, Chin-Chang Huang… in European Journal of Nuclear Medicine and M… (2012)

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  8. No Access

    Article

    Perfusion-like template and standardized normalization-based brain image analysis using 18F-florbetapir (AV-45/Amyvid) PET

    Amyloid positron emission tomography (PET) is an important noninvasive method for detecting amyloid burden in Alzheimer’s disease (AD) patients. As amyloid PET images have limited anatomical information, magne...

    Ing-Tsung Hsiao, Chin-Chang Huang… in European Journal of Nuclear Medicine and M… (2013)

  9. No Access

    Article

    Increased brain amyloid deposition in patients with a lifetime history of major depression: evidenced on 18F-florbetapir (AV-45/Amyvid) positron emission tomography

    The literature suggests that a history of depression is associated with an increased risk of develo** Alzheimer’s disease (AD). The aim of this study was to examine brain amyloid accumulation in patients wit...

    Kuan-Yi Wu, Ing-Tsung Hsiao… in European Journal of Nuclear Medicine and M… (2014)

  10. No Access

    Article

    Beta-amyloid deposition and cognitive function in patients with major depressive disorder with different subtypes of mild cognitive impairment: 18F-florbetapir (AV-45/Amyvid) PET study

    The objective of this study was to evaluate the amyloid burden, as assessed by 18F-florbetapir (AV-45/Amyvid) positron emission tomography PET, in patients with major depressive disorder (MDD) with different subt...

    Kuan-Yi Wu, Chia-Yih Liu, Cheng-Sheng Chen… in European Journal of Nuclear Medicine and M… (2016)

  11. No Access

    Article

    Imaging characteristic of dual-phase 18F-florbetapir (AV-45/Amyvid) PET for the concomitant detection of perfusion deficits and beta-amyloid deposition in Alzheimer’s disease and mild cognitive impairment

    We investigated dual-phase 18F-florbetapir (AV-45/Amyvid) PET imaging for the concomitant detection of brain perfusion deficits and beta-amyloid deposition in patients with Alzheimer’s disease (AD) and amnestic m...

    Kun-Ju Lin, Ing-Tsung Hsiao, Jung-Lung Hsu… in European Journal of Nuclear Medicine and M… (2016)

  12. Article

    Open Access

    Beta-amyloid deposition in patients with major depressive disorder with differing levels of treatment resistance: a pilot study

    Lack of treatment response in patients with late-life depression is common. The role of brain beta-amyloid (Aβ) deposition in treatment outcome in subjects with late-life depression remains unclear. The presen...

    Peng Li, Ing-Tsung Hsiao, Chia-Yih Liu, Chia-Hsiang Chen, She-Yao Huang… in EJNMMI Research (2017)

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  13. No Access

    Article

    [18F]FP-(+)-DTBZ PET study in a lactacystin-treated rat model of Parkinson disease

    Lactacystin has been used to establish rodent models of Parkinson disease (PD), with cerebral α-synuclein inclusions. This study evaluated the uptake of [18F]9-fluoropropyl-(+)-dihydrotetrabenazine ([18F]FP-(+)-D...

    Chi-Chang Weng, Siao-Lan Huang, Zi-An Chen, Kun-Ju Lin… in Annals of Nuclear Medicine (2017)

  14. Article

    Open Access

    Visualization of ischemic stroke-related changes on 18F-THK-5351 positron emission tomography

    The 18F-THK-5351 radiotracer has been used to detect the in vivo tau protein distribution in patients with tauopathy, such as Alzheimer’s disease and corticobasal syndrome. In addition, 18F-THK-5351 can also moni...

    Kuo-Lun Huang, Jung-Lung Hsu, Kun-Ju Lin, Chien-Hung Chang, Yi-Ming Wu… in EJNMMI Research (2018)

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  15. No Access

    Article

    Detection of Alzheimer’s disease using ECD SPECT images by transfer learning from FDG PET

    To develop a practical method to rapidly utilize a deep learning model to automatically extract image features based on a small number of SPECT brain perfusion images in general clinics to objectively evaluate...

    Yu-Ching Ni, Fan-Pin Tseng, Ming-Chyi Pai, Ing-Tsung Hsiao… in Annals of Nuclear Medicine (2021)

  16. Article

    Open Access

    Human biodistribution and radiation dosimetry for the tau tracer [18F]Florzolotau in healthy subjects

    Tau pathology plays a crucial role in neurodegeneration diseases including Alzheimer’s disease (AD) and non-AD diseases such as progressive supranuclear palsy. Tau positron emission tomography (PET) is an in-v...

    Kun-Ju Lin, Shao-Yi Huang, Kuo-Lun Huang… in EJNMMI Radiopharmacy and Chemistry (2024)

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