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  1. Article

    Open Access

    Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance

    Posttranslational modification dramatically enhances protein complexity, but the function and precise mechanism of novel lysine acylation modifications remain unknown. Chemoresistance remains a daunting challe...

    Yan He, Can-Can Zheng, **g Yang, Shu-Jun Li, Tao-Yang Xu, **an Wei… in Cell Discovery (2023)

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  2. Article

    Open Access

    Targeting PI3K/Akt signal transduction for cancer therapy

    The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a crucial role in various cellular processes and is aberrantly activated in cancers, contributing to the occurrence and progression of tumors. Examini...

    Yan He, Miao Miao Sun, Guo Geng Zhang… in Signal Transduction and Targeted Therapy (2021)

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